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UniProt Q9H5I1

Histone-lysine N-methyltransferase SUV39H2 (Q9H5I1)

Histone-lysine N-methyltransferase SUV39H2 (UniProt Q9H5I1), EC 2.1.1.43: 5 experimental structures on GenesisL1, 3 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9H5I1
Protein
Histone-lysine N-methyltransferase SUV39H2
EC
2.1.1.43
Experimental structures
5
Predicted models
0
Ligands
3
Pockets
6 · 1 record with a druggable one

Structures

5 records of Q9H5I1 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2R3AMethyltransferase domain of human suppressor of variegation 3-9 homolog 2x-ray diffractionA——
2R3AMethyltransferase domain of human suppressor of variegation 3-9 homolog 2x-ray diffractionA——
6P0RMethyltransferase domain of human suppressor of variegation 3-9 homolog 2 (SUV39H2) in complex with…x-ray diffractionA, BNM4, ZN, UNX6 (best 0.74)
6P0RMethyltransferase domain of human suppressor of variegation 3-9 homolog 2 (SUV39H2) in complex with…x-ray diffractionA, BNM4, ZN, UNX—
Q9H5I1AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase SUV39H2 (Q9H5I1)———

Ligands

  • NM4 · (3S)-1-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]-N-[(pyridin-4-yl)methyl]pyrrolidin-3-amine · in 2 records
  • UNX · Unknown atom or ion · in 2 records
  • ZN · Zinc ion · in 2 records

Elsewhere

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