UniProt Q9H4M7
Pleckstrin homology domain-containing family A member 4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (UniProt Q9H4M7): 5 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H4M7
- Protein
- Pleckstrin homology domain-containing family A member 4
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
6 records of Q9H4M7 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1UPQ | Crystal structure of the pleckstrin homology (PH) domain of PEPP1 | x-ray diffraction | A | — | — |
| 1UPQ | Crystal structure of the pleckstrin homology (pH) domain of PEPP1 | x-ray diffraction | A | — | — |
| 1UPR | Crystal structure of the PEPP1 pleckstrin homology domain in complex with Inositol… | x-ray diffraction | A | — | — |
| 1UPR | Crystal structure of the PEPP1 pleckstrin homology domain in complex with inositol… | x-ray diffraction | A | — | — |
| 8OIO | Crystal structure of the kelch domain of human KLHL12 in complex with PLEKHA4 peptide | x-ray diffraction | F, G, H, E | — | 1 (best 0.46) |
| Q9H4M7 | AlphaFold monomer V2.0 prediction for pleckstrin homology domain- containing family a member 4… | predicted | A | — | 5 (best 0.62) |
Experiment against prediction
- 1UPQ chain A against the predicted model Q9H4M7: TM-score 0.99, RMSD 0.44 Å
- 1UPQ chain A against the predicted model Q9H4M7: TM-score 0.99, RMSD 0.44 Å
- 1UPR chain A against the predicted model Q9H4M7: TM-score 0.98, RMSD 0.64 Å
- 1UPR chain A against the predicted model Q9H4M7: TM-score 0.98, RMSD 0.64 Å
- 8OIO chain E against the predicted model Q9H4M7: TM-score 0.76, RMSD 0.31 Å
- 8OIO chain G against the predicted model Q9H4M7: TM-score 0.66, RMSD 0.43 Å
- 8OIO chain F against the predicted model Q9H4M7: TM-score 0.61, RMSD 0.47 Å
- 8OIO chain H against the predicted model Q9H4M7: TM-score 0.61, RMSD 0.61 Å
Elsewhere
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