UniProt Q9H477
Ribokinase (Q9H477)
Ribokinase (UniProt Q9H477), EC 2.7.1.15: 19 experimental structures and 1 predicted model on GenesisL1, 10 ligands bound, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H477
- Protein
- Ribokinase
- EC
- 2.7.1.15
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 10
- Pockets
- 32 · 8 records with a druggable one
Structures
20 records of Q9H477 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FV7 | Crystal structure of human ribokinase | x-ray diffraction | A, B | NA, MG, ADP, UNX | 3 (best 0.74) |
| 2FV7 | Crystal structure of human ribokinase | x-ray diffraction | A, B | — | — |
| 5BYC | Crystal structure of human ribokinase in C2 spacegroup | x-ray diffraction | A, B | — | — |
| 5BYD | Crystal structure of human ribokinase in P21 spacegroup | x-ray diffraction | A, B | NA, K | 4 (best 0.69) |
| 5BYD | Crystal structure of human ribokinase in P21 spacegroup | x-ray diffraction | A, B | — | — |
| 5BYE | Crystal structure of human ribokinase in P212121 spacegroup | x-ray diffraction | A, B | NA, CL | 5 (best 0.71) |
| 5BYE | Crystal structure of human ribokinase in P212121 spacegroup | x-ray diffraction | A, B | — | — |
| 5BYF | Crystal structure of human ribokinase in complex with AMP | x-ray diffraction | A, B | — | — |
| 5BYF | Crystal structure of human ribokinase in complex with AMP | x-ray diffraction | A, B | — | — |
| 5C3Y | Structure of human ribokinase crystallized with amppnp | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 5C3Z | Crystal structure of human ribokinase in complex with AMPPCP in C2 spacegroup | x-ray diffraction | A, B | ACP, NA, CL | 2 (best 0.68) |
| 5C3Z | Crystal structure of human ribokinase in complex with amppcp in C2 spacegroup | x-ray diffraction | A, B | — | — |
| 5C40 | Crystal structure of human ribokinase in complex with AMPPCP in P21 spacegroup | x-ray diffraction | A, B | ACP, NA, PO4 | 4 (best 0.67) |
| 5C40 | Crystal structure of human ribokinase in complex with amppcp in P21 spacegroup | x-ray diffraction | A, B | — | — |
| 5C41 | Crystal structure of human ribokinase in complex with amppcp in P21 spacegroup and with 4 protomers | x-ray diffraction | A, B, C, D | — | — |
| 6WJZ | Crystal structure of human ribokinase in complex with AMPCP | x-ray diffraction | A, B | A12, NA, MG | 4 (best 0.69) |
| 6WJZ | Crystal structure of human ribokinase in complex with ampcp | x-ray diffraction | A, B | A12, NA | — |
| 6WK0 | Crystal structure of human ribokinase in complex with AMPPCP and ribose | x-ray diffraction | A, B, C, D | ACP, NA, RIB | 8 (best 0.72) |
| 6WK0 | Crystal structure of human ribokinase in complex with amppcp and ribose | x-ray diffraction | A, B, C, D | ACP, NA, RIB | — |
| Q9H477 | AlphaFold monomer V2.0 prediction for ribokinase (Q9H477) | predicted | A | — | 2 (best 0.63) |
Ligands
- NA · Sodium ion · in 9 records
- ACP · Phosphomethylphosphonic acid adenylate ester · in 4 records
- A12 · Phosphomethylphosphonic acid adenosyl ester · in 2 records
- CL · Chloride ion · in 2 records
- MG · Magnesium ion · in 2 records
- RIB · alpha-D-ribofuranose · in 2 records
- ADP · Adenosine-5'-diphosphate · in 1 record
- K · Potassium ion · in 1 record
- PO4 · Phosphate ion · in 1 record
- UNX · Unknown atom or ion · in 1 record
Experiment against prediction
- 5C3Y chain A against the predicted model Q9H477: TM-score 0.99, RMSD 0.48 Å
- 2FV7 chain A against the predicted model Q9H477: TM-score 0.99, RMSD 0.60 Å
- 2FV7 chain A against the predicted model Q9H477: TM-score 0.99, RMSD 0.60 Å
- 6WJZ chain B against the predicted model Q9H477: TM-score 0.98, RMSD 0.64 Å
- 6WJZ chain B against the predicted model Q9H477: TM-score 0.98, RMSD 0.64 Å
- 5C3Y chain D against the predicted model Q9H477: TM-score 0.98, RMSD 0.68 Å
- 5C3Y chain C against the predicted model Q9H477: TM-score 0.98, RMSD 0.46 Å
- 5BYF chain A against the predicted model Q9H477: TM-score 0.98, RMSD 0.63 Å
- 5BYF chain A against the predicted model Q9H477: TM-score 0.98, RMSD 0.63 Å
- 5BYF chain B against the predicted model Q9H477: TM-score 0.98, RMSD 0.67 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.