UniProt Q9H461
Frizzled-8 (Q9H461)
Frizzled-8 (UniProt Q9H461): 7 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H461
- Protein
- Frizzled-8
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 11 · 1 record with a druggable one
Structures
8 records of Q9H461 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UN5 | Frizzled-8 complex with designed surrogate Wnt agonist, crystal form 1 | x-ray diffraction | B, A | — | 3 (best 0.38) |
| 5UN5 | Frizzled-8 complex with designed surrogate wnt agonist, crystal form 1 | x-ray diffraction | B, A | — | — |
| 5UN6 | Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset | x-ray diffraction | A, B, C, D | — | — |
| 5UN6 | Frizzled-8 complex with designed surrogate wnt agonist, A1 dataset | x-ray diffraction | A, B, C, D | — | — |
| 6NDZ | Designed repeat protein in complex with Fz8 | x-ray diffraction | A, C, E | — | 7 (best 0.79) |
| 6NDZ | Designed repeat protein in complex with FZ8 | x-ray diffraction | A, C, E | — | — |
| 8X0T | Frizzled8 CRD in complex with pF8_AC3 Fab | x-ray diffraction | A | — | 1 (best 0.38) |
| Q9H461 | AlphaFold monomer V2.0 prediction for frizzled-8 (Q9H461) | predicted | A | — | — |
Experiment against prediction
- 5UN6 chain C against the predicted model Q9H461: TM-score 0.98, RMSD 0.55 Å
- 5UN6 chain C against the predicted model Q9H461: TM-score 0.98, RMSD 0.55 Å
- 5UN6 chain B against the predicted model Q9H461: TM-score 0.98, RMSD 0.62 Å
- 5UN6 chain B against the predicted model Q9H461: TM-score 0.98, RMSD 0.62 Å
- 5UN5 chain A against the predicted model Q9H461: TM-score 0.98, RMSD 0.62 Å
- 5UN5 chain A against the predicted model Q9H461: TM-score 0.98, RMSD 0.62 Å
- 5UN6 chain A against the predicted model Q9H461: TM-score 0.98, RMSD 0.61 Å
- 5UN6 chain A against the predicted model Q9H461: TM-score 0.98, RMSD 0.61 Å
- 6NDZ chain C against the predicted model Q9H461: TM-score 0.98, RMSD 0.69 Å
- 6NDZ chain C against the predicted model Q9H461: TM-score 0.98, RMSD 0.69 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.