UniProt Q9H2X9
potassium-chloride cotransporter 2 (Q9H2X9)
potassium-chloride cotransporter 2 (UniProt Q9H2X9): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H2X9
- Protein
- potassium-chloride cotransporter 2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 31 · 2 records with a druggable one
Structures
5 records of Q9H2X9 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6M23 | Overall structure of KCC2 | electron microscopy | A, B | NAG, K, CL | — |
| 6M23 | Overall structure of KCC2 | electron microscopy | A, B | NAG, K, CL | — |
| 7D8Z | human potassium-chloride co-transporter KCC2 | electron microscopy | B, A | NAG | 20 (best 0.81) |
| 7D8Z | Human potassium-chloride co-transporter KCC2 | electron microscopy | B, A | NAG | — |
| Q9H2X9 | AlphaFold monomer V2.0 prediction for solute carrier family 12 member 5 (Q9H2X9) | predicted | A | — | 11 (best 0.78) |
Ligands
Experiment against prediction
- 6M23 chain A against the predicted model Q9H2X9: TM-score 0.95, RMSD 2.44 Å
- 6M23 chain A against the predicted model Q9H2X9: TM-score 0.95, RMSD 2.44 Å
- 7D8Z chain B against the predicted model Q9H2X9: TM-score 0.95, RMSD 2.44 Å
- 7D8Z chain B against the predicted model Q9H2X9: TM-score 0.95, RMSD 2.44 Å
Elsewhere
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