UniProt Q9H211
DNA replication factor Cdt1 (Q9H211)
DNA replication factor Cdt1 (UniProt Q9H211): 8 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H211
- Protein
- DNA replication factor Cdt1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 16 · 3 records with a druggable one
Structures
9 records of Q9H211 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LE8 | The protein complex for DNA replication | solution nmr | B | — | — |
| 2LE8 | The protein complex for DNA replication | solution nmr | B | — | — |
| 2WVR | Human Cdt1:Geminin complex | x-ray diffraction | C | — | — |
| 2WVR | Human CDT1:GEMININ complex | x-ray diffraction | C | — | — |
| 6QCG | PCNA complex with Cdt1 N-terminal PIP-box peptide | x-ray diffraction | I, G, H, J, K, L | — | 13 (best 0.84) |
| 6QCG | PCNA complex with CDT1 N-terminal pip-box peptide | x-ray diffraction | I, G, H, J, K, L | — | — |
| 8S0E | H. sapiens OCCM bound to double stranded DNA | electron microscopy | 8 | — | 2 (best 0.77) |
| 8S0F | H. sapiens OC1M bound to double stranded DNA | electron microscopy | 8 | — | 1 (best 0.78) |
| Q9H211 | AlphaFold monomer V2.0 prediction for DNA replication factor CDT1 (Q9H211) | predicted | A | — | — |
Experiment against prediction
- 2WVR chain C against the predicted model Q9H211: TM-score 0.94, RMSD 1.29 Å
- 2WVR chain C against the predicted model Q9H211: TM-score 0.94, RMSD 1.29 Å
- 8S0E chain 8 against the predicted model Q9H211: TM-score 0.51, RMSD 0.66 Å
- 8S0F chain 8 against the predicted model Q9H211: TM-score 0.51, RMSD 0.71 Å
- 6QCG chain I against the predicted model Q9H211: TM-score 0.48, RMSD 1.00 Å
- 6QCG chain I against the predicted model Q9H211: TM-score 0.48, RMSD 1.00 Å
- 6QCG chain K against the predicted model Q9H211: TM-score 0.43, RMSD 1.45 Å
- 6QCG chain K against the predicted model Q9H211: TM-score 0.43, RMSD 1.45 Å
- 6QCG chain L against the predicted model Q9H211: TM-score 0.43, RMSD 2.25 Å
- 6QCG chain L against the predicted model Q9H211: TM-score 0.43, RMSD 2.25 Å
Elsewhere
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