UniProt Q9H165
B-cell lymphoma/leukemia 11A (Q9H165)
B-cell lymphoma/leukemia 11A (UniProt Q9H165): 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H165
- Protein
- B-cell lymphoma/leukemia 11A
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 5 records with a druggable one
Structures
13 records of Q9H165 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VTB | Crystal structure of RBBP4 bound to BCL11a peptide | x-ray diffraction | B | — | 1 (best 0.59) |
| 5VTB | Crystal structure of RBBP4 bound to BCL11A peptide | x-ray diffraction | B | — | — |
| 6KI6 | Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region | x-ray diffraction | A, B | ZN | 3 (best 0.76) |
| 6KI6 | Crystal structure of BCL11A in complex with gamma-globin -115 hpfh region | x-ray diffraction | A, B | ZN | — |
| 6U9Q | Crystal Structure Analysis of DNA-BCL11A Znf domain complex | x-ray diffraction | A | ZN, PO4, MG | 3 (best 0.59) |
| 6U9Q | Crystal structure analysis of DNA-BCL11A znf domain complex | x-ray diffraction | A | ZN, PO4, MG | — |
| 8DTN | The complex of nanobody 6101 with BCL11A ZF6 | x-ray diffraction | B, D, F, H | ZN, MG | 8 (best 0.73) |
| 8DTU | The complex of nanobody 5344N74D with BCL11A ZF6. | x-ray diffraction | C | ZN | — |
| 8THO | Solution structure of the zinc finger repeat domain of BCL11A (ZnF456) | solution nmr | A | ZN | — |
| 8TLO | Crystal Structure Analysis of BCL11A in complex with DNA | x-ray diffraction | A | ZN | 3 (best 0.60) |
| 9B4P | Tetramer Formation of the BCL11A ZF0 Domain | x-ray diffraction | B, C, A, D, E, F, G, H, I, J | ZN | 2 (best 0.43) |
| 9BV0 | NMR structure of the Z0 CCHC zinc-finger of transcription repressor Bcl11A | solution nmr | A | ZN | — |
| Q9H165 | AlphaFold monomer V2.0 prediction for B-cell LYMPHOMA/LEUKEMIA 11A (Q9H165) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6KI6 chain A against the predicted model Q9H165: TM-score 0.94, RMSD 0.91 Å
- 6KI6 chain A against the predicted model Q9H165: TM-score 0.94, RMSD 0.91 Å
- 8TLO chain A against the predicted model Q9H165: TM-score 0.91, RMSD 1.22 Å
- 6U9Q chain A against the predicted model Q9H165: TM-score 0.89, RMSD 1.64 Å
- 6U9Q chain A against the predicted model Q9H165: TM-score 0.89, RMSD 1.64 Å
- 9B4P chain D against the predicted model Q9H165: TM-score 0.85, RMSD 0.52 Å
- 9B4P chain E against the predicted model Q9H165: TM-score 0.83, RMSD 0.75 Å
- 6KI6 chain B against the predicted model Q9H165: TM-score 0.82, RMSD 1.28 Å
- 6KI6 chain B against the predicted model Q9H165: TM-score 0.82, RMSD 1.28 Å
- 9B4P chain J against the predicted model Q9H165: TM-score 0.79, RMSD 0.63 Å
Elsewhere
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