UniProt Q9H081
Protein MIS12 homolog (Q9H081)
Protein MIS12 homolog (UniProt Q9H081): 6 experimental structures and 1 predicted model on GenesisL1, 37 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H081
- Protein
- Protein MIS12 homolog
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 37 · 4 records with a druggable one
Structures
7 records of Q9H081 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LSJ | CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX | x-ray diffraction | A, C | — | 14 (best 0.75) |
| 5LSJ | Crystal structure of the human kinetochore MIS12-cenp-C delta-HEAD2 complex | x-ray diffraction | A, C | — | — |
| 5LSK | Crystal structure of the human kinetochore MIS12-cenp-C complex | x-ray diffraction | A | — | 2 (best 0.67) |
| 5LSK | Crystal structure of the human kinetochore MIS12-cenp-C complex | x-ray diffraction | A | — | — |
| 8PPR | Structure of the human outer kinetochore KMN network complex | electron microscopy | M | — | 10 (best 0.72) |
| 8Q5H | Human KMN network (outer kinetochore) | electron microscopy | A | — | 11 (best 0.85) |
| Q9H081 | AlphaFold monomer V2.0 prediction for protein MIS12 homolog (Q9H081) | predicted | A | — | — |
Experiment against prediction
- 5LSJ chain A against the predicted model Q9H081: TM-score 0.51, RMSD 2.29 Å
- 5LSJ chain A against the predicted model Q9H081: TM-score 0.51, RMSD 2.29 Å
- 5LSK chain A against the predicted model Q9H081: TM-score 0.50, RMSD 1.74 Å
- 5LSK chain A against the predicted model Q9H081: TM-score 0.50, RMSD 1.74 Å
- 8PPR chain M against the predicted model Q9H081: TM-score 0.50, RMSD 2.28 Å
- 8Q5H chain A against the predicted model Q9H081: TM-score 0.48, RMSD 2.71 Å
Elsewhere
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