UniProt Q9H078
Isoform 2 of Caseinolytic peptidase B protein homolog (Q9H078)
Isoform 2 of Caseinolytic peptidase B protein homolog (UniProt Q9H078), EC 3.6.1.-: 5 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 42 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9H078
- Protein
- Isoform 2 of Caseinolytic peptidase B protein homolog
- EC
- 3.6.1.-
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 42 · 2 records with a druggable one
Structures
6 records of Q9H078 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7US2 | PARL-cleaved Skd3 (human ClpB) E455Q Nucleotide Binding Domain hexamer bound to ATPgammaS, open… | electron microscopy | A, B, C, D, E, F | AGS, MG | 20 (best 0.75) |
| 7XBK | Structure and mechanism of a mitochondrial AAA+ disaggregase CLPB | electron microscopy | A, B, C, D, E, F, G, H, I | ATP, MG | 20 (best 0.79) |
| 7XC5 | Crystal structure of the ANK domain of CLPB | x-ray diffraction | A | — | — |
| 8DEH | Ankyrin domain of SKD3 | x-ray diffraction | A | — | 1 (best 0.29) |
| 8FDS | Ankyrin domain of SKD3 isoform 2 | x-ray diffraction | A | — | 1 (best 0.44) |
| Q9H078 | AlphaFold monomer V2.0 prediction for caseinolytic peptidase B protein homolog (Q9H078) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7XC5 chain A against the predicted model Q9H078: TM-score 0.98, RMSD 0.73 Å
- 7XBK chain D against the predicted model Q9H078: TM-score 0.95, RMSD 1.59 Å
- 7US2 chain F against the predicted model Q9H078: TM-score 0.95, RMSD 1.79 Å
- 7XBK chain E against the predicted model Q9H078: TM-score 0.95, RMSD 1.66 Å
- 7XBK chain C against the predicted model Q9H078: TM-score 0.95, RMSD 1.78 Å
- 7US2 chain E against the predicted model Q9H078: TM-score 0.94, RMSD 1.74 Å
- 7US2 chain A against the predicted model Q9H078: TM-score 0.94, RMSD 1.75 Å
- 7US2 chain B against the predicted model Q9H078: TM-score 0.94, RMSD 1.77 Å
- 7XBK chain B against the predicted model Q9H078: TM-score 0.94, RMSD 1.79 Å
- 7US2 chain C against the predicted model Q9H078: TM-score 0.94, RMSD 1.81 Å
Elsewhere
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