UniProt Q9GZS3
WD repeat-containing protein 61 (Q9GZS3)
WD repeat-containing protein 61 (UniProt Q9GZS3): 18 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9GZS3
- Protein
- WD repeat-containing protein 61
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 14 · 7 records with a druggable one
Structures
19 records of Q9GZS3 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3OW8 | Crystal Structure of the WD repeat-containing protein 61 | x-ray diffraction | A, B, C, D | — | — |
| 3OW8 | Crystal structure of the wd repeat-containing protein 61 | x-ray diffraction | A, B, C, D | — | — |
| 6GMH | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | electron microscopy | W | — | — |
| 6GMH | Structure of activated transcription complex pol II-dsif-paf-SPT6 | electron microscopy | W | — | — |
| 6TED | Structure of complete, activated transcription complex pol II-dsif- paf-SPT6 uncovers allosteric… | electron microscopy | W | — | — |
| 7OOP | Pol II-csb-csa-DDB1-uvssa-paf-SPT6 (structure 3) | electron microscopy | Y | — | — |
| 7OPC | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 4) | electron microscopy | Y | — | — |
| 7OPD | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 5) | electron microscopy | Y | — | — |
| 7QDR | Apo human ski complex in the closed state | electron microscopy | C, D | — | — |
| 7QDS | Apo human SKI complex in the open state | electron microscopy | C, D | — | 8 (best 0.83) |
| 7QDS | Apo human ski complex in the open state | electron microscopy | C, D | — | — |
| 7QDY | RNA-bound human ski complex | electron microscopy | C, D | — | — |
| 7QDZ | 80S-bound human ski complex in the closed state | electron microscopy | C, D | — | — |
| 7UNC | Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome | electron microscopy | W | — | 1 (best 0.76) |
| 7UND | Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) | electron microscopy | W | — | 1 (best 0.83) |
| 8A3Y | Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex | electron microscopy | W | — | 1 (best 0.84) |
| 9EGY | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-nucleosome, bp +27 | electron microscopy | W | — | 1 (best 0.83) |
| 9EH2 | RNA polymerase II-DSIF-SPT6-PAF1c-TFIIS-IWS1-SETD2-FACT nucleosome upstream | electron microscopy | W | — | 1 (best 0.84) |
| Q9GZS3 | AlphaFold monomer V2.0 prediction for wd repeat-containing protein 61 (Q9GZS3) | predicted | A | — | 1 (best 0.80) |
Experiment against prediction
- 3OW8 chain A against the predicted model Q9GZS3: TM-score 0.99, RMSD 0.47 Å
- 3OW8 chain A against the predicted model Q9GZS3: TM-score 0.99, RMSD 0.47 Å
- 3OW8 chain B against the predicted model Q9GZS3: TM-score 0.99, RMSD 0.48 Å
- 3OW8 chain B against the predicted model Q9GZS3: TM-score 0.99, RMSD 0.48 Å
- 3OW8 chain C against the predicted model Q9GZS3: TM-score 0.98, RMSD 0.94 Å
- 3OW8 chain C against the predicted model Q9GZS3: TM-score 0.98, RMSD 0.94 Å
- 7QDS chain D against the predicted model Q9GZS3: TM-score 0.97, RMSD 1.13 Å
- 7OOP chain Y against the predicted model Q9GZS3: TM-score 0.97, RMSD 1.18 Å
- 7OPC chain Y against the predicted model Q9GZS3: TM-score 0.97, RMSD 1.18 Å
- 7OPD chain Y against the predicted model Q9GZS3: TM-score 0.97, RMSD 1.18 Å
Elsewhere
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