UniProt Q9GUI1
N-acylethanolamine-hydrolyzing acid amidase alpha-subunit (Q9GUI1)
N-acylethanolamine-hydrolyzing acid amidase alpha-subunit (UniProt Q9GUI1), EC 3.5.1.60: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, druggability and experiment…
- UniProt
- Q9GUI1
- Protein
- N-acylethanolamine-hydrolyzing acid amidase alpha-subunit
- EC
- 3.5.1.60
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 21 · 2 records with a druggable one
Structures
3 records of Q9GUI1 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6DY3 | Caenorhabditis elegans N-acylethanolamine-hydrolyzing acid amidase (NAAA) ortholog | x-ray diffraction | A, B, C, D, E, F, G, H | NAG, FUC | 16 (best 0.71) |
| 6DY3 | Caenorhabditis elegans N-acylethanolamine-hydrolyzing acid amidase (naaa) ortholog | x-ray diffraction | A, B, C, D, E, F, G, H | NAG, FUC | — |
| Q9GUI1 | AlphaFold monomer V2.0 prediction for N-acylethanolamine-hydrolyzing acid amidase (Q9GUI1) | predicted | A | — | 5 (best 0.82) |
Ligands
Experiment against prediction
- 6DY3 chain H against the predicted model Q9GUI1: TM-score 0.94, RMSD 1.53 Å
- 6DY3 chain F against the predicted model Q9GUI1: TM-score 0.93, RMSD 1.36 Å
- 6DY3 chain B against the predicted model Q9GUI1: TM-score 0.93, RMSD 1.56 Å
- 6DY3 chain B against the predicted model Q9GUI1: TM-score 0.93, RMSD 1.56 Å
- 6DY3 chain D against the predicted model Q9GUI1: TM-score 0.93, RMSD 1.57 Å
- 6DY3 chain G against the predicted model Q9GUI1: TM-score 0.80, RMSD 2.20 Å
- 6DY3 chain E against the predicted model Q9GUI1: TM-score 0.80, RMSD 2.22 Å
- 6DY3 chain E against the predicted model Q9GUI1: TM-score 0.80, RMSD 2.22 Å
- 6DY3 chain A against the predicted model Q9GUI1: TM-score 0.79, RMSD 2.33 Å
- 6DY3 chain A against the predicted model Q9GUI1: TM-score 0.79, RMSD 2.33 Å
Elsewhere
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