UniProt Q9FNN5
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (Q9FNN5)
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (UniProt Q9FNN5), EC 7.1.1.2: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment…
- UniProt
- Q9FNN5
- Protein
- NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
- EC
- 7.1.1.2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 3 records with a druggable one
Structures
7 records of Q9FNN5 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7AQR | Cryo-EM structure of Arabidopsis thaliana Complex-I (peripheral arm) | electron microscopy | F | FMN, SF4 | 5 (best 0.80) |
| 7AQR | Cryo-EM structure of arabidopsis thaliana complex-I (peripheral arm) | electron microscopy | F | FMN, SF4 | — |
| 7AR7 | Cryo-EM structure of arabidopsis thaliana complex-I (open conformation) | electron microscopy | F | FMN, SF4 | — |
| 7AR8 | Cryo-EM structure of arabidopsis thaliana complex-I (closed conformation) | electron microscopy | F | FMN, SF4 | — |
| 7ARB | Cryo-EM structure of arabidopsis thaliana complex-I (complete composition) | electron microscopy | F | FMN, SF4 | — |
| 8BED | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI peripheral tip) | electron microscopy | F | FMN, SF4 | 9 (best 0.80) |
| Q9FNN5 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial… | predicted | A | — | 2 (best 0.77) |
Ligands
Experiment against prediction
- 8BED chain F against the predicted model Q9FNN5: TM-score 0.99, RMSD 0.63 Å
- 7ARB chain F against the predicted model Q9FNN5: TM-score 0.99, RMSD 0.68 Å
- 7AQR chain F against the predicted model Q9FNN5: TM-score 0.99, RMSD 0.68 Å
- 7AQR chain F against the predicted model Q9FNN5: TM-score 0.99, RMSD 0.68 Å
- 7AR7 chain F against the predicted model Q9FNN5: TM-score 0.99, RMSD 0.81 Å
- 7AR8 chain F against the predicted model Q9FNN5: TM-score 0.98, RMSD 0.95 Å
Elsewhere
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