UniProt Q9FLM8
DNA-directed RNA polymerases II, IV and V subunit 12 (Q9FLM8)
DNA-directed RNA polymerases II, IV and V subunit 12 (UniProt Q9FLM8): 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9FLM8
- Protein
- DNA-directed RNA polymerases II, IV and V subunit 12
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 5 records with a druggable one
Structures
8 records of Q9FLM8 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EU0 | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | electron microscopy | L | ZN | 1 (best 0.77) |
| 7EU0 | The cryo-EM structure of a. thaliana pol IV-RDR2 backtracked complex | electron microscopy | L | ZN | — |
| 7EU1 | The cryo-EM structure of a. thaliana pol IV-RDR2 holoenzyme | electron microscopy | L | ZN | — |
| 8HYJ | A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex | electron microscopy | L | ZN | 2 (best 0.84) |
| 8XMB | NTP-bound Pol IV transcription elongation complex | electron microscopy | L | ZN | 2 (best 0.73) |
| 8XMD | Pre-translocated Pol IV transcription elongation complex | electron microscopy | L | ZN | 1 (best 0.87) |
| 8XME | Backtracked Pol IV transcription elongation complex | electron microscopy | L | ZN | 1 (best 0.73) |
| Q9FLM8 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases II, IV and V subunit 12 (Q9FLM8) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 7 records
Experiment against prediction
- 8HYJ chain L against the predicted model Q9FLM8: TM-score 0.80, RMSD 1.08 Å
- 7EU0 chain L against the predicted model Q9FLM8: TM-score 0.73, RMSD 1.40 Å
- 7EU0 chain L against the predicted model Q9FLM8: TM-score 0.73, RMSD 1.40 Å
- 8XMB chain L against the predicted model Q9FLM8: TM-score 0.73, RMSD 1.44 Å
- 8XMD chain L against the predicted model Q9FLM8: TM-score 0.73, RMSD 1.44 Å
- 8XME chain L against the predicted model Q9FLM8: TM-score 0.72, RMSD 1.47 Å
- 7EU1 chain L against the predicted model Q9FLM8: TM-score 0.72, RMSD 1.67 Å
Elsewhere
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