UniProt Q9FJ98
DNA-directed RNA polymerases II, IV and V subunit 6A (Q9FJ98)
DNA-directed RNA polymerases II, IV and V subunit 6A (UniProt Q9FJ98): 8 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9FJ98
- Protein
- DNA-directed RNA polymerases II, IV and V subunit 6A
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 9 · 5 records with a druggable one
Structures
9 records of Q9FJ98 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EU0 | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | electron microscopy | F | — | — |
| 7EU0 | The cryo-EM structure of a. thaliana pol IV-RDR2 backtracked complex | electron microscopy | F | — | — |
| 7EU1 | The cryo-EM structure of a. thaliana pol IV-RDR2 holoenzyme | electron microscopy | F | — | — |
| 8HYJ | A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex | electron microscopy | F | — | 4 (best 0.81) |
| 8XMB | NTP-bound Pol IV transcription elongation complex | electron microscopy | F | — | 1 (best 0.74) |
| 8XMC | Post-translocated Pol IV transcription elongation complex | electron microscopy | F | — | 1 (best 0.72) |
| 8XMD | Pre-translocated Pol IV transcription elongation complex | electron microscopy | F | — | 1 (best 0.72) |
| 8XME | Backtracked Pol IV transcription elongation complex | electron microscopy | F | — | 1 (best 0.72) |
| Q9FJ98 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases II, IV and V subunit 6A (Q9FJ98) | predicted | A | — | 1 (best 0.40) |
Experiment against prediction
- 8XMC chain F against the predicted model Q9FJ98: TM-score 0.97, RMSD 0.56 Å
- 8XMD chain F against the predicted model Q9FJ98: TM-score 0.96, RMSD 0.61 Å
- 8XME chain F against the predicted model Q9FJ98: TM-score 0.96, RMSD 0.62 Å
- 8XMB chain F against the predicted model Q9FJ98: TM-score 0.96, RMSD 0.63 Å
- 7EU0 chain F against the predicted model Q9FJ98: TM-score 0.95, RMSD 0.84 Å
- 7EU0 chain F against the predicted model Q9FJ98: TM-score 0.95, RMSD 0.84 Å
- 7EU1 chain F against the predicted model Q9FJ98: TM-score 0.93, RMSD 0.91 Å
- 8HYJ chain F against the predicted model Q9FJ98: TM-score 0.86, RMSD 1.55 Å
Elsewhere
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