UniProt Q9EVR0
L-lactate dehydrogenase (Q9EVR0)
L-lactate dehydrogenase (UniProt Q9EVR0), EC 1.1.1.27: 3 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9EVR0
- Protein
- L-lactate dehydrogenase
- EC
- 1.1.1.27
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 22 · 2 records with a druggable one
Structures
4 records of Q9EVR0 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7NAY | Crystal structure of lactate dehydrogenase from Selenomonas ruminantium with NADH. | x-ray diffraction | A | NAD, BO3 | 2 (best 0.65) |
| 7NAY | Crystal structure of lactate dehydrogenase from selenomonas ruminantium with NADH. | x-ray diffraction | A | NAD, BO3 | — |
| 8Q3C | Structure of Selenomonas ruminantium lactate dehydrogenase I85R mutant | x-ray diffraction | H, N, U, a | PO4, NO3, CL | 20 (best 0.85) |
| Q9EVR0 | AlphaFold monomer V2.0 prediction for L-lactate dehydrogenase (Q9EVR0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8Q3C chain a against the predicted model Q9EVR0: TM-score 0.98, RMSD 0.96 Å
- 8Q3C chain N against the predicted model Q9EVR0: TM-score 0.98, RMSD 1.05 Å
- 8Q3C chain H against the predicted model Q9EVR0: TM-score 0.98, RMSD 1.06 Å
- 8Q3C chain U against the predicted model Q9EVR0: TM-score 0.97, RMSD 1.09 Å
- 7NAY chain A against the predicted model Q9EVR0: TM-score 0.95, RMSD 1.48 Å
- 7NAY chain A against the predicted model Q9EVR0: TM-score 0.95, RMSD 1.48 Å
Elsewhere
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