UniProt Q9EQZ5
Prostaglandin reductase 1 (Q9EQZ5)
Prostaglandin reductase 1 (UniProt Q9EQZ5): 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9EQZ5
- Protein
- Prostaglandin reductase 1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
9 records of Q9EQZ5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1V3T | Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase | x-ray diffraction | A, B | — | — |
| 1V3T | Crystal structure of leukotriene B4 12- HYDROXYDEHYDROGENASE/15-oxo-prostaglandin 13-reductase | x-ray diffraction | A, B | — | — |
| 1V3U | Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase in… | x-ray diffraction | A, B | — | — |
| 1V3U | Crystal structure of leukotriene B4 12- HYDROXYDEHYDROGENASE/15-oxo-prostaglandin 13-reductase in… | x-ray diffraction | A, B | — | — |
| 1V3V | Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase… | x-ray diffraction | A, B | — | — |
| 1V3V | Crystal structure of leukotriene B4 12- HYDROXYDEHYDROGENASE/15-oxo-prostaglandin 13-reductase… | x-ray diffraction | A, B | — | — |
| 2DM6 | Crystal structure of anti-configuration of indomethacin and leukotriene B4… | x-ray diffraction | A, B | — | — |
| 2DM6 | Crystal structure of anti-configuration of indomethacin and leukotriene B4… | x-ray diffraction | A, B | — | — |
| Q9EQZ5 | AlphaFold monomer V2.0 prediction for prostaglandin reductase 1 (Q9EQZ5) | predicted | A | — | 2 (best 0.75) |
Experiment against prediction
- 1V3V chain A against the predicted model Q9EQZ5: TM-score 0.98, RMSD 0.74 Å
- 1V3V chain A against the predicted model Q9EQZ5: TM-score 0.98, RMSD 0.74 Å
- 1V3T chain A against the predicted model Q9EQZ5: TM-score 0.98, RMSD 0.74 Å
- 1V3T chain A against the predicted model Q9EQZ5: TM-score 0.98, RMSD 0.74 Å
- 2DM6 chain A against the predicted model Q9EQZ5: TM-score 0.98, RMSD 0.74 Å
- 2DM6 chain A against the predicted model Q9EQZ5: TM-score 0.98, RMSD 0.74 Å
- 1V3T chain B against the predicted model Q9EQZ5: TM-score 0.99, RMSD 0.78 Å
- 1V3T chain B against the predicted model Q9EQZ5: TM-score 0.99, RMSD 0.78 Å
- 1V3V chain B against the predicted model Q9EQZ5: TM-score 0.99, RMSD 0.78 Å
- 1V3V chain B against the predicted model Q9EQZ5: TM-score 0.99, RMSD 0.78 Å
Elsewhere
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