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UniProt Q9EQG7

Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (Q9EQG7)

Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (UniProt Q9EQG7), EC 3.1.-.-: 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 5 pockets. Binding sites, druggability and experiment…

UniProt
Q9EQG7
Protein
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5
EC
3.1.-.-
Experimental structures
4
Predicted models
1
Ligands
6
Pockets
5 · 2 records with a druggable one

Structures

5 records of Q9EQG7 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
5VENMurine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5)x-ray diffractionA, BNAG, BMA, MAN, FUC, ZN4 (best 0.69)
5VENMurine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5)x-ray diffractionA, BNAG, BMA, MAN, FUC, ZN—
5VEOMurine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5), inactive (T72A), in…x-ray diffractionANAG, FUC, ZN, AMP1 (best 0.63)
5VEOMurine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5), inactive (T72A), in…x-ray diffractionANAG, FUC, ZN, AMP—
Q9EQG7AlphaFold monomer V2.0 prediction for ectonucleotide PYROPHOSPHATASE/PHOSPHODIESTERASE family…predictedA——

Ligands

  • FUC · alpha-L-fucopyranose · in 4 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • ZN · Zinc ion · in 4 records
  • AMP · Adenosine monophosphate · in 2 records
  • BMA · beta-D-mannopyranose · in 2 records
  • MAN · alpha-D-mannopyranose · in 2 records

Experiment against prediction

Elsewhere

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