UniProt Q9EPK8

Transient receptor potential cation channel subfamily V member 4 (Q9EPK8)

Transient receptor potential cation channel subfamily V member 4 (UniProt Q9EPK8): 5 experimental structures on GenesisL1, 2 ligands bound, 80 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: Q9EPK8
Protein: Transient receptor potential cation channel subfamily V member 4
Experimental structures: 5
Predicted models: 0
Ligands: 2
Pockets: 80 · 4 records with a druggable one

Structures

5 records of Q9EPK8 in the MolNFT archive: 5 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8J1B	GSK101 and Ruthenium Red bound state of mTRPV4	electron microscopy	A, B, C, D	XQ3, R2R	20 (best 0.85)
8J1D	Cryo-EM structure of apo state mTRPV4	electron microscopy	A, B, C, D	—	20 (best 0.83)
8J1F	GSK101 bound state of mTRPV4	electron microscopy	A, B, C, D	XQ3	20 (best 0.82)
8JKM	RN-1747 bound state of mTRPV4	electron microscopy	A, B, C, D	—	20 (best 0.81)
Q9EPK8	AlphaFold monomer V2.0 prediction for transient receptor potential cation channel subfamily V…	—		—	—

Ligands

XQ3 · N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide · in 2 records
R2R · ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) · in 1 record

Elsewhere

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