UniProt Q9D8T2
Gasdermin-D (Q9D8T2)
Gasdermin-D (UniProt Q9D8T2): 8 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9D8T2
- Protein
- Gasdermin-D
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 16 · 2 records with a druggable one
Structures
9 records of Q9D8T2 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AO3 | Crystal structure of the murine gasdermin D C-terminal domain | x-ray diffraction | A, B, C, D | — | 5 (best 0.68) |
| 6AO3 | Crystal structure of the murine gasdermin D C-terminal domain | x-ray diffraction | A, B, C, D | — | — |
| 6KMV | caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain | x-ray diffraction | C, D, G, H, K, L, O, P, S, T, W, X, a, b, e, f | — | — |
| 6KMV | Caspase-11 C254A P22/P10 in complex with mouse gsdmd-C domain | x-ray diffraction | C, D, G, H, K, L, O, P, S, T, W, X, a, b, e, f | — | — |
| 6N9N | Crystal structure of murine GSDMD | x-ray diffraction | A, B | — | — |
| 6N9N | Crystal structure of murine gsdmd | x-ray diffraction | A, B | — | — |
| 6VIE | Structure of caspase-1 in complex with gasdermin D | x-ray diffraction | C, D | — | 11 (best 0.78) |
| 6VIE | Structure of caspase-1 in complex with gasdermin D | x-ray diffraction | C, D | — | — |
| Q9D8T2 | AlphaFold monomer V2.0 prediction for gasdermin-D (Q9D8T2) | predicted | A | — | — |
Experiment against prediction
- 6KMV chain f against the predicted model Q9D8T2: TM-score 0.98, RMSD 0.84 Å
- 6KMV chain D against the predicted model Q9D8T2: TM-score 0.98, RMSD 0.86 Å
- 6KMV chain D against the predicted model Q9D8T2: TM-score 0.98, RMSD 0.86 Å
- 6KMV chain K against the predicted model Q9D8T2: TM-score 0.97, RMSD 0.90 Å
- 6KMV chain C against the predicted model Q9D8T2: TM-score 0.97, RMSD 0.91 Å
- 6KMV chain C against the predicted model Q9D8T2: TM-score 0.97, RMSD 0.91 Å
- 6KMV chain W against the predicted model Q9D8T2: TM-score 0.97, RMSD 0.93 Å
- 6KMV chain T against the predicted model Q9D8T2: TM-score 0.97, RMSD 0.93 Å
- 6KMV chain a against the predicted model Q9D8T2: TM-score 0.97, RMSD 0.96 Å
- 6KMV chain a against the predicted model Q9D8T2: TM-score 0.97, RMSD 0.96 Å
Elsewhere
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