UniProt Q9D7W5
Mediator of RNA polymerase II transcription subunit 8 (Q9D7W5)
Mediator of RNA polymerase II transcription subunit 8 (UniProt Q9D7W5): 4 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9D7W5
- Protein
- Mediator of RNA polymerase II transcription subunit 8
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
5 records of Q9D7W5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6W1S | Atomic model of the mammalian Mediator complex | electron microscopy | E | — | 1 (best 0.81) |
| 6W1S | Atomic model of the mammalian mediator complex | electron microscopy | E | — | — |
| 8T1I | Atomic model of the mammalian Mediator complex with MED26 subunit | electron microscopy | E | — | — |
| 8T1L | Atomic model of the mammalian mouse Mediator complex with CKM module | electron microscopy | E | — | — |
| Q9D7W5 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 8 (Q9D7W5) | predicted | A | — | — |
Experiment against prediction
- 6W1S chain E against the predicted model Q9D7W5: TM-score 0.69, RMSD 3.46 Å
- 6W1S chain E against the predicted model Q9D7W5: TM-score 0.69, RMSD 3.46 Å
- 8T1L chain E against the predicted model Q9D7W5: TM-score 0.64, RMSD 3.29 Å
- 8T1I chain E against the predicted model Q9D7W5: TM-score 0.53, RMSD 4.41 Å
Elsewhere
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