UniProt Q9D2Y4
Mixed lineage kinase domain-like protein (Q9D2Y4)
Mixed lineage kinase domain-like protein (UniProt Q9D2Y4): 6 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9D2Y4
- Protein
- Mixed lineage kinase domain-like protein
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
7 records of Q9D2Y4 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4BTF | Structure of MLKL | x-ray diffraction | A | — | — |
| 4BTF | Structure of mlkl | x-ray diffraction | A | — | — |
| 4M68 | Crystal structure of the mouse MLKL kinase-like domain | x-ray diffraction | A | — | — |
| 4M68 | Crystal structure of the mouse mlkl kinase-like domain | x-ray diffraction | A | — | — |
| 4M69 | Crystal structure of the mouse RIP3-MLKL complex | x-ray diffraction | B | — | — |
| 4M69 | Crystal structure of the mouse RIP3-mlkl complex | x-ray diffraction | B | — | — |
| Q9D2Y4 | AlphaFold monomer V2.0 prediction for mixed lineage kinase domain- like protein (Q9D2Y4) | predicted | A | — | 6 (best 0.76) |
Experiment against prediction
- 4M68 chain A against the predicted model Q9D2Y4: TM-score 0.99, RMSD 0.91 Å
- 4M68 chain A against the predicted model Q9D2Y4: TM-score 0.99, RMSD 0.91 Å
- 4BTF chain A against the predicted model Q9D2Y4: TM-score 0.98, RMSD 1.17 Å
- 4BTF chain A against the predicted model Q9D2Y4: TM-score 0.98, RMSD 1.17 Å
- 4M69 chain B against the predicted model Q9D2Y4: TM-score 0.91, RMSD 2.30 Å
- 4M69 chain B against the predicted model Q9D2Y4: TM-score 0.91, RMSD 2.30 Å
Elsewhere
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