UniProt Q9CW03
Structural maintenance of chromosomes protein 3 (Q9CW03)
Structural maintenance of chromosomes protein 3 (UniProt Q9CW03): 4 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9CW03
- Protein
- Structural maintenance of chromosomes protein 3
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 23 · 4 records with a druggable one
Structures
5 records of Q9CW03 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WD5 | SMC hinge heterodimer (Mouse) | x-ray diffraction | B | — | 3 (best 0.78) |
| 2WD5 | Smc hinge heterodimer (mouse) | x-ray diffraction | B | — | 3 (best 0.78) |
| 7DG5 | Crystal structure of mouse Smc1-Smc3 hinge domain containing a D574Y mutation | x-ray diffraction | B, D | — | 7 (best 0.83) |
| 7DG5 | Crystal structure of mouse SMC1-SMC3 hinge domain containing a D574Y mutation | x-ray diffraction | B, D | — | — |
| Q9CW03 | AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes protein 3 (Q9CW03) | predicted | A | — | 10 (best 0.53) |
Experiment against prediction
- 2WD5 chain B against the predicted model Q9CW03: TM-score 0.95, RMSD 1.19 Å
- 2WD5 chain B against the predicted model Q9CW03: TM-score 0.95, RMSD 1.19 Å
- 7DG5 chain D against the predicted model Q9CW03: TM-score 0.94, RMSD 1.40 Å
- 7DG5 chain D against the predicted model Q9CW03: TM-score 0.94, RMSD 1.40 Å
- 7DG5 chain B against the predicted model Q9CW03: TM-score 0.94, RMSD 1.43 Å
- 7DG5 chain B against the predicted model Q9CW03: TM-score 0.94, RMSD 1.43 Å
Elsewhere
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