UniProt Q9CQ54
NADH dehydrogenase [ubiquinone] 1 subunit C2 (Q9CQ54)
NADH dehydrogenase [ubiquinone] 1 subunit C2 (UniProt Q9CQ54): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q9CQ54
- Protein
- NADH dehydrogenase [ubiquinone] 1 subunit C2
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 18 · 6 records with a druggable one
Structures
15 records of Q9CQ54 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | d | 3PE, CDL | 3 (best 0.85) |
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | d | 3PE, CDL | — |
| 6G72 | Mouse mitochondrial complex I in the deactive state | electron microscopy | d | — | — |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a | electron microscopy | d | CDL | — |
| 6ZTQ | Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at 3.0 a | electron microscopy | d | CDL | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | electron microscopy | d | 3PE, CDL | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2 a | electron microscopy | d | 3PE, CDL | — |
| 7AK6 | Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a | electron microscopy | d | CDL | — |
| 7B93 | Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at 3.0 a | electron microscopy | d | CDL | — |
| 8IAQ | Respiratory complex Membrane domain of CI, focused map of type I, Wild type mouse under… | electron microscopy | d | CDL | 4 (best 0.84) |
| 8IBD | Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature | electron microscopy | d | 3PE, CDL | 3 (best 0.85) |
| 8IC4 | Respiratory complex Membrane domain of CI, focus-refined of type I, PERK -/- mouse under cold… | electron microscopy | d | CDL | 3 (best 0.84) |
| 8PW6 | C respirasome from murine liver | electron microscopy | d1 | CDL, 3PE | 2 (best 0.85) |
| 8RGR | Closed Complex I from murine liver | electron microscopy | d | CDL, 3PE | 2 (best 0.87) |
| Q9CQ54 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 subunit C2 (Q9CQ54) | predicted | A | — | 1 (best 0.44) |
Ligands
Experiment against prediction
- 8IBD chain d against the predicted model Q9CQ54: TM-score 0.93, RMSD 1.42 Å
- 8IAQ chain d against the predicted model Q9CQ54: TM-score 0.93, RMSD 1.43 Å
- 8IC4 chain d against the predicted model Q9CQ54: TM-score 0.92, RMSD 1.45 Å
- 8RGR chain d against the predicted model Q9CQ54: TM-score 0.92, RMSD 1.51 Å
- 8PW6 chain d1 against the predicted model Q9CQ54: TM-score 0.92, RMSD 1.49 Å
- 7B93 chain d against the predicted model Q9CQ54: TM-score 0.92, RMSD 1.55 Å
- 6ZTQ chain d against the predicted model Q9CQ54: TM-score 0.91, RMSD 1.56 Å
- 6ZR2 chain d against the predicted model Q9CQ54: TM-score 0.91, RMSD 1.56 Å
- 7AK5 chain d against the predicted model Q9CQ54: TM-score 0.91, RMSD 1.46 Å
- 7AK5 chain d against the predicted model Q9CQ54: TM-score 0.91, RMSD 1.46 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.