UniProt Q9BZJ8
G-protein coupled receptor 61 (Q9BZJ8)
G-protein coupled receptor 61 (UniProt Q9BZJ8): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BZJ8
- Protein
- G-protein coupled receptor 61
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 21 · 4 records with a druggable one
Structures
4 records of Q9BZJ8 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8KGK | Cryo-EM structure of the GPR61-Gs complex | electron microscopy | A | — | 4 (best 0.74) |
| 8TB0 | Cryo-EM Structure of GPR61-G protein complex stabilized by scFv16 | electron microscopy | R | — | 8 (best 0.81) |
| 8TB7 | Cryo-EM Structure of GPR61- | electron microscopy | R | ZOB | 5 (best 0.72) |
| Q9BZJ8 | AlphaFold monomer V2.0 prediction for G-protein coupled receptor 61 (Q9BZJ8) | predicted | A | — | 4 (best 0.62) |
Ligands
- ZOB · 6-{[(3,5-difluoropyridin-4-yl)methyl]amino}-N-(4-ethoxy-6-methylpyrimidin-2-yl)-2-methoxy-N-(2-methoxyethyl)pyridine-3-sulfonamide · in 1 record
Experiment against prediction
- 8KGK chain A against the predicted model Q9BZJ8: TM-score 0.97, RMSD 1.06 Å
- 8TB7 chain R against the predicted model P0ABE7: TM-score 0.35, RMSD 2.27 Å
- 8TB7 chain R against the predicted model Q9BZJ8: TM-score 0.68, RMSD 2.08 Å
- 8TB0 chain R against the predicted model Q9BZJ8: TM-score 0.52, RMSD 2.59 Å
- 8TB0 chain R against the predicted model P63092: TM-score 0.42, RMSD 2.78 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.