UniProt Q9BYT8
Neurolysin, mitochondrial (Q9BYT8)
Neurolysin, mitochondrial (UniProt Q9BYT8), EC 3.4.24.16: 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 82 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BYT8
- Protein
- Neurolysin, mitochondrial
- EC
- 3.4.24.16
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 82 · 6 records with a druggable one
Structures
8 records of Q9BYT8 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LUZ | Structure of Human Neurolysin (E475Q) in complex with neurotensin peptide products | x-ray diffraction | A, B | ZN, CL | 18 (best 0.90) |
| 5LUZ | Structure of human neurolysin (E475Q) in complex with neurotensin peptide products | x-ray diffraction | A, B | ZN, CL | — |
| 5LV0 | Structure of Human Neurolysin (E475Q) in complex with amyloid-beta 35-40 peptide product | x-ray diffraction | A, B | ZN, CL | 20 (best 0.88) |
| 5LV0 | Structure of human neurolysin (E475Q) in complex with amyloid-beta 35- 40 peptide product | x-ray diffraction | A, B | ZN, CL | — |
| 8VJV | Structure of Human Neurolysin in complex with dynorphin A8(1-8) peptide | x-ray diffraction | A | ZN, CL | 6 (best 0.86) |
| 8VJW | Structure of Human Neurolysin in complex with angiotensin I peptide | x-ray diffraction | A, B | ZN | 15 (best 0.90) |
| 8VJY | Structure of Human Neurolysin in complex with Neurotensin peptide | x-ray diffraction | A, C | ZN | 15 (best 0.89) |
| Q9BYT8 | AlphaFold monomer V2.0 prediction for neurolysin, mitochondrial (Q9BYT8) | predicted | A | — | 8 (best 0.81) |
Ligands
Experiment against prediction
- 5LUZ chain A against the predicted model Q9BYT8: TM-score 0.98, RMSD 1.31 Å
- 5LUZ chain A against the predicted model Q9BYT8: TM-score 0.98, RMSD 1.31 Å
- 5LV0 chain A against the predicted model Q9BYT8: TM-score 0.98, RMSD 1.45 Å
- 5LV0 chain A against the predicted model Q9BYT8: TM-score 0.98, RMSD 1.45 Å
- 8VJY chain A against the predicted model Q9BYT8: TM-score 0.97, RMSD 1.48 Å
- 5LUZ chain B against the predicted model Q9BYT8: TM-score 0.97, RMSD 1.59 Å
- 5LUZ chain B against the predicted model Q9BYT8: TM-score 0.97, RMSD 1.59 Å
- 8VJV chain A against the predicted model Q9BYT8: TM-score 0.97, RMSD 1.61 Å
- 8VJW chain A against the predicted model Q9BYT8: TM-score 0.96, RMSD 1.75 Å
- 5LV0 chain B against the predicted model Q9BYT8: TM-score 0.96, RMSD 1.77 Å
Elsewhere
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