UniProt Q9BYT3
Serine/threonine-protein kinase 33 (Q9BYT3)
Serine/threonine-protein kinase 33 (UniProt Q9BYT3), EC 2.7.11.1: 1 experimental structure and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9BYT3
- Protein
- Serine/threonine-protein kinase 33
- EC
- 2.7.11.1
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 2 records with a druggable one
Structures
2 records of Q9BYT3 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8VF6 | Crystal structure of Serine/threonine-protein kinase 33 (STK33) Kinase Domain in complex with… | x-ray diffraction | A, B | A1AAY | 3 (best 0.65) |
| Q9BYT3 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase 33 (Q9BYT3) | predicted | A | — | 2 (best 0.77) |
Ligands
- A1AAY · {3-[([1,1'-biphenyl]-2-yl)ethynyl]-1H-indazol-5-yl}[(3R)-3-(dimethylamino)pyrrolidin-1-yl]methanone · in 1 record
Experiment against prediction
- 8VF6 chain B against the predicted model Q9BYT3: TM-score 0.94, RMSD 1.44 Å
- 8VF6 chain A against the predicted model Q9BYT3: TM-score 0.94, RMSD 1.32 Å
Elsewhere
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