UniProt Q9BYM8
RanBP-type and C3HC4-type zinc finger-containing protein 1 (Q9BYM8)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (UniProt Q9BYM8), EC 2.3.2.31: 13 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 33 pockets. Binding sites, druggability and experiment…
- UniProt
- Q9BYM8
- Protein
- RanBP-type and C3HC4-type zinc finger-containing protein 1
- EC
- 2.3.2.31
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 33 · 4 records with a druggable one
Structures
14 records of Q9BYM8 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CRC | Solution structure of the zf-RanBP domain of the protein HBV associated factor | solution nmr | A | — | — |
| 2CRC | Solution structure of the zf-ranbp domain of the protein HBV associated factor | solution nmr | A | — | — |
| 2LGY | Ubiquitin-like domain from HOIL-1 | solution nmr | A | — | — |
| 2LGY | Ubiquitin-like domain from hoil-1 | solution nmr | A | — | — |
| 4DBG | Crystal structure of HOIL-1L-UBL complexed with a HOIP-UBA derivative | x-ray diffraction | A | — | — |
| 4DBG | Crystal structure of hoil-1L-ubl complexed with a hoip-uba derivative | x-ray diffraction | A | — | — |
| 7V8E | Crystal structure of IPAH1.4 lrr domain bound to hoil-1L ubl domain. | x-ray diffraction | C, D | — | — |
| 7YUI | Crystal structure of HOIL-1L(195-423) in complex with the linear tetra-ubiquitin | x-ray diffraction | B | ZN | 9 (best 0.71) |
| 7YUJ | Crystal structure of HOIL-1L(365-510) | x-ray diffraction | A, B | ZN | 2 (best 0.81) |
| 8EAZ | HOIL-1/E2-Ub/Ub transthiolation complex | x-ray diffraction | A, B | ZN | 17 (best 0.83) |
| 8K6Q | Crystal structure of HOIL-1L LTM domain | x-ray diffraction | B, D, A, C | — | 1 (best 0.39) |
| 9EGV | HOIL-1 RING2 domain bound to ubiquitin | x-ray diffraction | A, B | ZN, CL, SO4 | 2 (best 0.51) |
| 9EGW | HOIL-1 RING2 domain bound to ubiquitin-maltose (maltose not modelled) | x-ray diffraction | A, B | ZN, CL, SO4 | 2 (best 0.49) |
| Q9BYM8 | AlphaFold monomer V2.0 prediction for ranbp-type and C3HC4-type zinc finger-containing protein 1… | predicted | A | — | — |
Ligands
Experiment against prediction
- 4DBG chain A against the predicted model Q9BYM8: TM-score 0.97, RMSD 0.57 Å
- 4DBG chain A against the predicted model Q9BYM8: TM-score 0.97, RMSD 0.57 Å
- 7V8E chain C against the predicted model Q9BYM8: TM-score 0.97, RMSD 0.66 Å
- 7V8E chain D against the predicted model Q9BYM8: TM-score 0.95, RMSD 0.91 Å
- 8K6Q chain D against the predicted model Q9BYM8: TM-score 0.93, RMSD 1.01 Å
- 8K6Q chain C against the predicted model Q9BYM8: TM-score 0.88, RMSD 0.91 Å
- 9EGV chain B against the predicted model Q9BYM8: TM-score 0.87, RMSD 1.37 Å
- 9EGW chain B against the predicted model Q9BYM8: TM-score 0.86, RMSD 1.49 Å
- 8EAZ chain B against the predicted model Q9BYM8: TM-score 0.85, RMSD 2.55 Å
- 8EAZ chain A against the predicted model Q9BYM8: TM-score 0.85, RMSD 2.69 Å
Elsewhere
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