UniProt Q9BY43

Charged multivesicular body protein 4a (Q9BY43)

Charged multivesicular body protein 4a (UniProt Q9BY43): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q9BY43
Protein: Charged multivesicular body protein 4a
Experimental structures: 4
Predicted models: 1
Pockets: 3 · 1 record with a druggable one

Structures

5 records of Q9BY43 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
3C3O	ALIX Bro1-domain:CHMIP4A co-crystal structure	x-ray diffraction	B	—	—
3C3O	Alix BRO1-DOMAIN:CHMIP4A co-crystal structure	x-ray diffraction	B	—	—
5MK1	Crystal structure of the His Domain Protein Tyrosine Phosphatase (HD-PTP/PTPN23) Bro1 domain…	x-ray diffraction	E, F, H, K	—	3 (best 0.76)
5MK1	Crystal structure of the his domain protein tyrosine phosphatase (hd- PTP/PTPN23) BRO1 domain…	x-ray diffraction	E, F, H, K	—	—
Q9BY43	AlphaFold monomer V2.0 prediction for charged multivesicular body protein 4A (Q9BY43)	predicted	A	—	—

Experiment against prediction

5MK1 chain F against the predicted model Q9BY43: TM-score 0.79, RMSD 0.29 Å
5MK1 chain F against the predicted model Q9BY43: TM-score 0.79, RMSD 0.29 Å
5MK1 chain H against the predicted model Q9BY43: TM-score 0.76, RMSD 0.30 Å
5MK1 chain H against the predicted model Q9BY43: TM-score 0.76, RMSD 0.30 Å
5MK1 chain K against the predicted model Q9BY43: TM-score 0.73, RMSD 0.34 Å
5MK1 chain K against the predicted model Q9BY43: TM-score 0.73, RMSD 0.34 Å
5MK1 chain E against the predicted model Q9BY43: TM-score 0.67, RMSD 0.51 Å
5MK1 chain E against the predicted model Q9BY43: TM-score 0.67, RMSD 0.51 Å
3C3O chain B against the predicted model Q9BY43: TM-score 0.59, RMSD 0.76 Å
3C3O chain B against the predicted model Q9BY43: TM-score 0.59, RMSD 0.76 Å

Elsewhere

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