UniProt Q9BUQ8
Probable ATP-dependent RNA helicase DDX23 (Q9BUQ8)
Probable ATP-dependent RNA helicase DDX23 (UniProt Q9BUQ8), EC 3.6.4.13: 17 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 26 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9BUQ8
- Protein
- Probable ATP-dependent RNA helicase DDX23
- EC
- 3.6.4.13
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 26 · 9 records with a druggable one
Structures
18 records of Q9BUQ8 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCR | 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | electron microscopy | F | — | — |
| 3JCR | 3D structure determination of the HUMAN*U4/U6.U5* tri-snrnp complex | electron microscopy | F | — | — |
| 4NHO | Structure of the spliceosomal DEAD-box protein Prp28 | x-ray diffraction | A | — | — |
| 4NHO | Structure of the spliceosomal dead-box protein PRP28 | x-ray diffraction | A | — | — |
| 6AH0 | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | electron microscopy | X | — | — |
| 6AH0 | The cryo-EM structure of the precusor of human pre-catalytic spliceosome (pre-B complex) | electron microscopy | X | — | — |
| 6QW6 | Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | electron microscopy | 5X | IHP | 2 (best 0.80) |
| 6QX9 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | electron microscopy | 5X | IHP | 1 (best 0.78) |
| 8H6E | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | electron microscopy | 4U | — | 2 (best 0.83) |
| 8Q7X | Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4) | electron microscopy | E | — | 4 (best 0.82) |
| 8Q91 | Structure of the human 20S U5 snRNP core | electron microscopy | D | — | 4 (best 0.76) |
| 8QPK | Cryo-EM Structure of Pre-B+5'ss Complex (core part) | electron microscopy | G | — | 4 (best 0.85) |
| 8R08 | Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | electron microscopy | G | — | 2 (best 0.86) |
| 8R09 | Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | electron microscopy | G | — | — |
| 8R0B | Cryo-EM structure of the cross-exon pre-B+ATP complex | electron microscopy | G | — | — |
| 8RM5 | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | electron microscopy | G | — | 2 (best 0.83) |
| 8Y6O | Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP… | electron microscopy | I | IHP | 5 (best 0.83) |
| Q9BUQ8 | AlphaFold monomer V2.0 prediction for probable ATP-dependent RNA helicase DDX23 (Q9BUQ8) | predicted | A | — | — |
Ligands
- IHP · Inositol hexakisphosphate · in 3 records
Experiment against prediction
- 8RM5 chain G against the predicted model Q9BUQ8: TM-score 0.96, RMSD 1.42 Å
- 8R09 chain G against the predicted model Q9BUQ8: TM-score 0.96, RMSD 1.45 Å
- 8Y6O chain I against the predicted model Q9BUQ8: TM-score 0.91, RMSD 2.90 Å
- 6QX9 chain 5X against the predicted model Q9BUQ8: TM-score 0.90, RMSD 2.72 Å
- 8R0B chain G against the predicted model Q9BUQ8: TM-score 0.90, RMSD 0.91 Å
- 8QPK chain G against the predicted model Q9BUQ8: TM-score 0.88, RMSD 1.52 Å
- 8Q91 chain D against the predicted model Q9BUQ8: TM-score 0.84, RMSD 1.09 Å
- 8H6E chain 4U against the predicted model Q9BUQ8: TM-score 0.81, RMSD 2.57 Å
- 6QW6 chain 5X against the predicted model Q9BUQ8: TM-score 0.73, RMSD 3.86 Å
- 8R08 chain G against the predicted model Q9BUQ8: TM-score 0.70, RMSD 3.39 Å
Elsewhere
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