UniProt Q9BUN8
Derlin-1 (Q9BUN8)
Derlin-1 (UniProt Q9BUN8): 7 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BUN8
- Protein
- Derlin-1
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 23 · 2 records with a druggable one
Structures
8 records of Q9BUN8 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GLF | Structural insights into the interaction of p97 N-terminal domain and SHP motif in Derlin-1… | x-ray diffraction | B, D, F, H | — | — |
| 5GLF | Structural insights into the interaction of P97 N-terminal domain and shp motif in derlin-1… | x-ray diffraction | B, D, F, H | — | — |
| 7CZB | The cryo-EM structure of the ERAD retrotranslocation channel formed by human Derlin-1 | electron microscopy | A, B, C, D | — | 17 (best 0.47) |
| 7CZB | The cryo-EM structure of the erad retrotranslocation channel formed by human derlin-1 | electron microscopy | A, B, C, D | — | — |
| 7Y4W | The cryo-EM structure of human ERAD retro-translocation complex | electron microscopy | W, X, Y, Z | — | — |
| 7Y53 | The cryo-EM structure of human ERAD retro-translocation complex | electron microscopy | W, X, Y, Z | — | 1 (best 0.75) |
| 7Y59 | The cryo-EM structure of human ERAD retro-translocation complex | electron microscopy | W, X, Y, Z | — | 5 (best 0.86) |
| Q9BUN8 | AlphaFold monomer V2.0 prediction for derlin-1 (Q9BUN8) | predicted | A | — | — |
Experiment against prediction
- 7CZB chain D against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.40 Å
- 7CZB chain D against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.40 Å
- 7CZB chain B against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.52 Å
- 7CZB chain B against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.52 Å
- 7CZB chain A against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.61 Å
- 7CZB chain A against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.61 Å
- 7CZB chain C against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.62 Å
- 7CZB chain C against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.62 Å
- 7Y4W chain Z against the predicted model Q9BUN8: TM-score 0.93, RMSD 1.80 Å
- 7Y4W chain X against the predicted model Q9BUN8: TM-score 0.92, RMSD 1.98 Å
Elsewhere
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