UniProt Q9BTT4
Mediator of RNA polymerase II transcription subunit 10 (Q9BTT4)
Mediator of RNA polymerase II transcription subunit 10 (UniProt Q9BTT4): 9 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BTT4
- Protein
- Mediator of RNA polymerase II transcription subunit 10
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 3 · 3 records with a druggable one
Structures
10 records of Q9BTT4 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EMF | Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | electron microscopy | J | — | 1 (best 0.80) |
| 7EMF | Human mediator (deletion of MED1-idr) in a tail-extended conformation | electron microscopy | J | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | j | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | j | — | — |
| 7ENJ | Human mediator (deletion of MED1-idr) in a tail-bent conformation (med-B) | electron microscopy | J | — | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | k | — | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | k | — | — |
| 8GXQ | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | electron microscopy | j | — | 1 (best 0.83) |
| 8TQW | Structure of human transcriptional Mediator complex | electron microscopy | J | — | 1 (best 0.82) |
| Q9BTT4 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 10… | predicted | A | — | — |
Experiment against prediction
- 7NVR chain k against the predicted model Q9BTT4: TM-score 0.82, RMSD 2.31 Å
- 7NVR chain k against the predicted model Q9BTT4: TM-score 0.82, RMSD 2.31 Å
- 7ENJ chain J against the predicted model Q9BTT4: TM-score 0.72, RMSD 3.03 Å
- 7EMF chain J against the predicted model Q9BTT4: TM-score 0.72, RMSD 3.03 Å
- 7EMF chain J against the predicted model Q9BTT4: TM-score 0.72, RMSD 3.03 Å
- 8GXQ chain j against the predicted model Q9BTT4: TM-score 0.72, RMSD 3.15 Å
- 8TQW chain J against the predicted model Q9BTT4: TM-score 0.70, RMSD 3.24 Å
- 7ENA chain j against the predicted model Q9BTT4: TM-score 0.69, RMSD 3.07 Å
- 7ENC chain j against the predicted model Q9BTT4: TM-score 0.69, RMSD 3.23 Å
Elsewhere
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