UniProt Q9B6E9
NADH-ubiquinone oxidoreductase chain 6 (Q9B6E9)
NADH-ubiquinone oxidoreductase chain 6 (UniProt Q9B6E9), EC 1.6.5.3, 7.1.1.2: 13 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9B6E9
- Protein
- NADH-ubiquinone oxidoreductase chain 6
- EC
- 1.6.5.3, 7.1.1.2
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 6 records with a druggable one
Structures
14 records of Q9B6E9 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GCS | Cryo-EM structure of respiratory complex I from Yarrowia lipolytica | electron microscopy | 6 | CDL | 3 (best 0.89) |
| 6GCS | Cryo-EM structure of respiratory complex I from yarrowia lipolytica | electron microscopy | 6 | CDL | — |
| 6H8K | Crystal structure of a variant (Q133C in PSST) of Yarrowia lipolytica complex I | x-ray diffraction | 6 | — | 3 (best 0.79) |
| 6RFQ | Cryo-EM structure of a respiratory complex I assembly intermediate with NDUFAF2 | electron microscopy | 6 | CDL, T7X, 3PE | 5 (best 0.89) |
| 6RFQ | Cryo-EM structure of a respiratory complex I assembly intermediate with NDUFAF2 | electron microscopy | 6 | CDL, T7X, 3PE | — |
| 6RFR | Cryo-EM structure of respiratory complex I from Yarrowia lipolytica at 3.2 A resolution | electron microscopy | 6 | CDL, 3PE, T7X | — |
| 6RFR | Cryo-EM structure of respiratory complex I from yarrowia lipolytica at 3.2 a resolution | electron microscopy | 6 | CDL, 3PE, T7X | — |
| 6RFS | Cryo-EM structure of a respiratory complex I mutant lacking NDUFS4 | electron microscopy | 6 | — | 3 (best 0.83) |
| 6RFS | Cryo-EM structure of a respiratory complex I mutant lacking NDUFS4 | electron microscopy | 6 | — | — |
| 6Y79 | Cryo-EM structure of a respiratory complex I F89A mutant | electron microscopy | 6 | CDL, T7X | 5 (best 0.86) |
| 6Y79 | Cryo-EM structure of a respiratory complex I F89A mutant | electron microscopy | 6 | CDL, T7X | — |
| 6YJ4 | Structure of Yarrowia lipolytica complex I at 2.7 A | electron microscopy | J | 3PE, CDL | 4 (best 0.89) |
| 6YJ4 | Structure of yarrowia lipolytica complex I at 2.7 a | electron microscopy | J | 3PE, CDL | — |
| Q9B6E9 | AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 6 (Q9B6E9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6H8K chain 6 against the predicted model Q9B6E9: TM-score 0.88, RMSD 1.85 Å
- 6RFS chain 6 against the predicted model Q9B6E9: TM-score 0.81, RMSD 2.35 Å
- 6RFS chain 6 against the predicted model Q9B6E9: TM-score 0.81, RMSD 2.35 Å
- 6Y79 chain 6 against the predicted model Q9B6E9: TM-score 0.76, RMSD 2.85 Å
- 6Y79 chain 6 against the predicted model Q9B6E9: TM-score 0.76, RMSD 2.85 Å
- 6RFR chain 6 against the predicted model Q9B6E9: TM-score 0.75, RMSD 2.98 Å
- 6RFR chain 6 against the predicted model Q9B6E9: TM-score 0.75, RMSD 2.98 Å
- 6RFQ chain 6 against the predicted model Q9B6E9: TM-score 0.75, RMSD 2.98 Å
- 6RFQ chain 6 against the predicted model Q9B6E9: TM-score 0.75, RMSD 2.98 Å
- 6YJ4 chain J against the predicted model Q9B6E9: TM-score 0.75, RMSD 3.14 Å
Elsewhere
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