UniProt Q99ZI6

Protein-ADP-ribose hydrolase (Q99ZI6)

Protein-ADP-ribose hydrolase (UniProt Q99ZI6), EC 3.2.1.-: 1 experimental structure and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q99ZI6
Protein: Protein-ADP-ribose hydrolase
EC: 3.2.1.-
Experimental structures: 1
Predicted models: 1
Ligands: 2
Pockets: 1 · 1 record with a druggable one

Structures

2 records of Q99ZI6 in the MolNFT archive: 1 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8RSM	Crystal structure of Streptococcus pyogenes macrodomain in complex with ADP-ribose	x-ray diffraction	A	ZN, AR6	1 (best 0.64)
Q99ZI6	AlphaFold monomer V2.0 prediction for protein-ADP-ribose hydrolase (Q99ZI6)	predicted	A	—	—

Ligands

AR6 · [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2R,3S,4R,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate · in 1 record
ZN · Zinc ion · in 1 record

Experiment against prediction

8RSM chain A against the predicted model Q99ZI6: TM-score 0.97, RMSD 1.16 Å

Elsewhere

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