UniProt Q99QS1
Extracellular Adherence Protein (Q99QS1)
Extracellular Adherence Protein (UniProt Q99QS1): 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 94 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99QS1
- Protein
- Extracellular Adherence Protein
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 94 · 11 records with a druggable one
Structures
14 records of Q99QS1 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YN3 | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to… | x-ray diffraction | A, B | — | — |
| 1YN3 | Crystal structures of eap domains from staphylococcus aureus reveal an unexpected homology to… | x-ray diffraction | A, B | — | — |
| 8D4O | Crystal Structure of the Neutrophil Serine Protease Inhibitor Eap1 from S. aureus | x-ray diffraction | A, B, C, D | NA | 5 (best 0.82) |
| 8D4Q | Crystal Structure of Neutrophil Elastase Inhibited by Eap1 from S. aureus | x-ray diffraction | C, D | — | 7 (best 0.74) |
| 8D4S | Crystal Structure of Cathepsin G Inhibited by Eap1 from S. aureus | x-ray diffraction | F, B, H, D | — | 7 (best 0.57) |
| 8D4U | Crystal Structure of Neutrophil Elastase Inhibited by Eap2 from S. aureus | x-ray diffraction | C, D | — | 4 (best 0.75) |
| 8D4V | Crystal Structure of Cathepsin G Inhibited by Eap2 from S. aureus | x-ray diffraction | B, D | — | 6 (best 0.50) |
| 8D7I | Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap1 from S. aureus | x-ray diffraction | B, E, H, K, N, Q | — | 18 (best 0.70) |
| 8D7K | Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap2 from S. aureus | x-ray diffraction | B, E, H, K | — | 12 (best 0.83) |
| 9ASS | Crystal Structure of Neutrophil Elastase Inhibited by Eap4 from S. aureus | x-ray diffraction | C | — | 2 (best 0.65) |
| 9ASX | BIFUNCTIONAL INHIBITION OF NEUTROPHIL ELASTASE AND CATHEPSIN G by Eap3 of S. aureus | x-ray diffraction | C | — | 4 (best 0.66) |
| 9ATK | BIFUNCTIONAL INHIBITION OF NEUTROPHIL ELASTASE AND CATHEPSIN G by Eap4 of S. aureus | x-ray diffraction | C, F, I, L | — | 19 (best 0.82) |
| 9ATU | Bifunctional Inhibition of Neutrophil Elastase by Eap4 from S. aureus | x-ray diffraction | B, E | — | 9 (best 0.80) |
| Q99QS1 | AlphaFold monomer V2.0 prediction for protein MAP (Q99QS1) | predicted | A | — | 1 (best 0.50) |
Ligands
- NA · Sodium ion · in 1 record
Experiment against prediction
- 8D4S chain H against the predicted model Q99QS1: TM-score 0.98, RMSD 0.48 Å
- 8D4S chain B against the predicted model Q99QS1: TM-score 0.98, RMSD 0.51 Å
- 8D4S chain F against the predicted model Q99QS1: TM-score 0.98, RMSD 0.51 Å
- 8D7I chain B against the predicted model Q99QS1: TM-score 0.98, RMSD 0.53 Å
- 8D4S chain D against the predicted model Q99QS1: TM-score 0.98, RMSD 0.52 Å
- 8D4Q chain C against the predicted model Q99QS1: TM-score 0.97, RMSD 0.61 Å
- 8D7K chain E against the predicted model Q99QS1: TM-score 0.97, RMSD 0.63 Å
- 8D7K chain K against the predicted model Q99QS1: TM-score 0.97, RMSD 0.63 Å
- 8D7K chain B against the predicted model Q99QS1: TM-score 0.97, RMSD 0.67 Å
- 8D4V chain B against the predicted model Q99QS1: TM-score 0.97, RMSD 0.69 Å
Elsewhere
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