UniProt Q99K74
Mediator of RNA polymerase II transcription subunit 24 (Q99K74)
Mediator of RNA polymerase II transcription subunit 24 (UniProt Q99K74): 4 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99K74
- Protein
- Mediator of RNA polymerase II transcription subunit 24
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 13 · 3 records with a druggable one
Structures
5 records of Q99K74 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6W1S | Atomic model of the mammalian Mediator complex | electron microscopy | S | — | 4 (best 0.87) |
| 6W1S | Atomic model of the mammalian mediator complex | electron microscopy | S | — | — |
| 8T1I | Atomic model of the mammalian Mediator complex with MED26 subunit | electron microscopy | S | — | 4 (best 0.85) |
| 8T1L | Atomic model of the mammalian mouse Mediator complex with CKM module | electron microscopy | S | — | 5 (best 0.86) |
| Q99K74 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 24… | predicted | A | — | — |
Experiment against prediction
- 6W1S chain S against the predicted model Q99K74: TM-score 0.95, RMSD 2.22 Å
- 6W1S chain S against the predicted model Q99K74: TM-score 0.95, RMSD 2.22 Å
- 8T1I chain S against the predicted model Q99K74: TM-score 0.94, RMSD 2.26 Å
- 8T1L chain S against the predicted model Q99K74: TM-score 0.94, RMSD 2.48 Å
Elsewhere
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