UniProt Q99958
Forkhead box protein C2 (Q99958)
Forkhead box protein C2 (UniProt Q99958): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99958
- Protein
- Forkhead box protein C2
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
11 records of Q99958 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D5V | Solution structure of the forkhead domain of the adipocyte-transcription factor freac-11 (S12) | solution nmr | A | — | — |
| 1D5V | Solution structure of the forkhead domain of the adipocyte- transcription factor freac-11 (S12) | solution nmr | A | — | — |
| 6AKO | Crystal Structure of FOXC2 DBD Bound to DBE2 DNA | x-ray diffraction | C | MG | 4 (best 0.53) |
| 6AKO | Crystal structure of FOXC2 dbd bound to DBE2 DNA | x-ray diffraction | C | MG | — |
| 6AKP | Crystal Structural of FOXC2 DNA binding domain bound to PC promoter | x-ray diffraction | C | MG | 2 (best 0.41) |
| 6AKP | Crystal structural of FOXC2 DNA binding domain bound to pc promoter | x-ray diffraction | C | MG | — |
| 6LBM | Crystal Structure of FOXC2-DBD bound to a palindromic DNA sequence | x-ray diffraction | C | MG | 3 (best 0.40) |
| 6LBM | Crystal structure of FOXC2-dbd bound to a palindromic DNA sequence | x-ray diffraction | C | MG | — |
| 6O3T | Structural basis of FOXC2 and DNA interactions | x-ray diffraction | A, B | — | — |
| 6O3T | Structural basis of FOXC2 and DNA interactions | x-ray diffraction | A, B | — | — |
| Q99958 | AlphaFold monomer V2.0 prediction for forkhead box protein C2 (Q99958) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 6 records
Experiment against prediction
- 6O3T chain B against the predicted model Q99958: TM-score 0.97, RMSD 0.48 Å
- 6O3T chain B against the predicted model Q99958: TM-score 0.97, RMSD 0.48 Å
- 6AKP chain C against the predicted model Q99958: TM-score 0.91, RMSD 1.66 Å
- 6AKP chain C against the predicted model Q99958: TM-score 0.91, RMSD 1.66 Å
- 6O3T chain A against the predicted model Q99958: TM-score 0.91, RMSD 1.53 Å
- 6O3T chain A against the predicted model Q99958: TM-score 0.91, RMSD 1.53 Å
- 6AKO chain C against the predicted model Q99958: TM-score 0.89, RMSD 1.78 Å
- 6AKO chain C against the predicted model Q99958: TM-score 0.89, RMSD 1.78 Å
- 6LBM chain C against the predicted model Q99958: TM-score 0.89, RMSD 2.15 Å
- 6LBM chain C against the predicted model Q99958: TM-score 0.89, RMSD 2.15 Å
Elsewhere
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