UniProt Q99728
Q99728
Q99728 (UniProt Q99728): 15 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99728
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 2
Structures
16 records of Q99728 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JM7 | Solution structure of the BRCA1/BARD1 RING-domain heterodimer | solution nmr | B | — | — |
| 1JM7 | Solution structure of the BRCA1/BARD1 ring-domain heterodimer | solution nmr | B | — | — |
| 2NTE | Crystal Structure of the BARD1 BRCT Domains | x-ray diffraction | A, B | — | — |
| 2NTE | Crystal structure of the BARD1 brct domains | x-ray diffraction | A, B | — | — |
| 2R1Z | Crystal Structure of the BARD1 BRCT Repeat | x-ray diffraction | A, B | — | — |
| 2R1Z | Crystal structure of the BARD1 brct repeat | x-ray diffraction | A, B | — | — |
| 3C5R | Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences | x-ray diffraction | A, B | — | — |
| 3C5R | Crystal structure of the BARD1 ankyrin repeat domain and its functional consequences | x-ray diffraction | A, B | — | — |
| 3FA2 | Crystal Structure of the BRCA1 Associated Ring Domain (BARD1) Tandem BRCT Domains | x-ray diffraction | A, B | — | — |
| 3FA2 | Crystal structure of the BRCA1 associated ring domain (BARD1) tandem brct domains | x-ray diffraction | A, B | — | — |
| 6M14 | Crystal structure of the BARD1 brct mutant | x-ray diffraction | B, A | SO4 | — |
| 7E8I | Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin | electron microscopy | K | — | — |
| 7JZV | Cryo-EM structure of the BRCA1-UBCH5C/BARD1 E3-E2 module bound to a nucleosome | electron microscopy | B | ZN | — |
| 7LYB | Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UBCH5C | electron microscopy | N | ZN | — |
| 7LYC | Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A LYS13 and… | electron microscopy | N | — | — |
| Q99728 | AlphaFold monomer V2.0 prediction for BRCA1-associated ring domain protein 1 (Q99728) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2R1Z chain A against the predicted model Q99728: TM-score 0.99, RMSD 0.48 Å
- 2R1Z chain A against the predicted model Q99728: TM-score 0.99, RMSD 0.48 Å
- 6M14 chain B against the predicted model Q99728: TM-score 0.99, RMSD 0.64 Å
- 2NTE chain B against the predicted model Q99728: TM-score 0.99, RMSD 0.66 Å
- 2NTE chain B against the predicted model Q99728: TM-score 0.99, RMSD 0.66 Å
- 3C5R chain B against the predicted model Q99728: TM-score 0.98, RMSD 0.53 Å
- 3C5R chain B against the predicted model Q99728: TM-score 0.98, RMSD 0.53 Å
- 2R1Z chain B against the predicted model Q99728: TM-score 0.98, RMSD 0.71 Å
- 2R1Z chain B against the predicted model Q99728: TM-score 0.98, RMSD 0.71 Å
- 3FA2 chain A against the predicted model Q99728: TM-score 0.98, RMSD 0.80 Å
Elsewhere
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