UniProt Q99717
Mothers against decapentaplegic homolog 5 (Q99717)
Mothers against decapentaplegic homolog 5 (UniProt Q99717): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99717
- Protein
- Mothers against decapentaplegic homolog 5
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
5 records of Q99717 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6FZS | Crystal structure of SMAD5-MH1 bound to the ggcgc site. | x-ray diffraction | A, B | ZN | — |
| 6TBZ | Crystal structure of the MH1 domain of SMAD5-SMAD3 chimera construct bound to the ggcgc site | x-ray diffraction | A | ZN | — |
| 6TCE | Crystal structure of the GGCT site-bound MH1 domain of Smad5 containing a GGGS insertion in the… | x-ray diffraction | A | ZN | — |
| 6TCE | Crystal structure of the ggct site-bound MH1 domain of SMAD5 containing a gggs insertion in the… | x-ray diffraction | A | ZN | — |
| Q99717 | AlphaFold monomer V2.0 prediction for mothers against decapentaplegic homolog 5 (Q99717) | predicted | A | — | 6 (best 0.57) |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 6TCE chain A against the predicted model Q99717: TM-score 0.95, RMSD 1.32 Å
- 6TCE chain A against the predicted model Q99717: TM-score 0.95, RMSD 1.32 Å
- 6TBZ chain A against the predicted model Q99717: TM-score 0.94, RMSD 0.88 Å
- 6FZS chain B against the predicted model Q99717: TM-score 0.84, RMSD 1.19 Å
- 6FZS chain A against the predicted model Q99717: TM-score 0.84, RMSD 1.22 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.