UniProt Q99626
Homeobox protein CDX-2 (Q99626)
Homeobox protein CDX-2 (UniProt Q99626): 6 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99626
- Protein
- Homeobox protein CDX-2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 6 · 2 records with a druggable one
Structures
7 records of Q99626 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LTY | Homeobox transcription factor CDX2 bound to methylated DNA | x-ray diffraction | K, M | — | 4 (best 0.72) |
| 5LTY | Homeobox transcription factor CDX2 bound to methylated DNA | x-ray diffraction | K, M | — | — |
| 6ES2 | Structure of CDX2-DNA(CAA) | x-ray diffraction | K, L | — | 2 (best 0.69) |
| 6ES2 | Structure of CDX2-DNA(CAA) | x-ray diffraction | K, L | — | — |
| 6ES3 | Structure of CDX2-DNA(TCG) | x-ray diffraction | K, M | — | — |
| 6ES3 | Structure of CDX2-DNA(TCG) | x-ray diffraction | K, M | — | — |
| Q99626 | AlphaFold monomer V2.0 prediction for homeobox protein cdx-2 (Q99626) | predicted | A | — | — |
Experiment against prediction
- 5LTY chain M against the predicted model Q99626: TM-score 0.94, RMSD 1.17 Å
- 5LTY chain M against the predicted model Q99626: TM-score 0.94, RMSD 1.17 Å
- 6ES2 chain K against the predicted model Q99626: TM-score 0.94, RMSD 1.17 Å
- 6ES2 chain K against the predicted model Q99626: TM-score 0.94, RMSD 1.17 Å
- 5LTY chain K against the predicted model Q99626: TM-score 0.93, RMSD 1.12 Å
- 5LTY chain K against the predicted model Q99626: TM-score 0.93, RMSD 1.12 Å
- 6ES2 chain L against the predicted model Q99626: TM-score 0.92, RMSD 1.23 Å
- 6ES2 chain L against the predicted model Q99626: TM-score 0.92, RMSD 1.23 Å
- 6ES3 chain K against the predicted model Q99626: TM-score 0.92, RMSD 1.16 Å
- 6ES3 chain K against the predicted model Q99626: TM-score 0.92, RMSD 1.16 Å
Elsewhere
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