UniProt Q99312
IMP-specific 5'-nucleotidase 1 (Q99312)
IMP-specific 5'-nucleotidase 1 (UniProt Q99312), EC 3.1.3.99: 1 experimental structure and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q99312
- Protein
- IMP-specific 5'-nucleotidase 1
- EC
- 3.1.3.99
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
2 records of Q99312 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8J6H | Structure and allosteric regulation of the inosine 5'-monophosphate-specific phosphatase ISN1 from… | x-ray diffraction | A, B, C, D | NOS | 20 (best 0.77) |
| Q99312 | AlphaFold monomer V2.0 prediction for imp-specific 5'-nucleotidase 1 (Q99312) | predicted | A | — | — |
Ligands
- NOS · Inosine · in 1 record
Experiment against prediction
- 8J6H chain B against the predicted model Q99312: TM-score 0.95, RMSD 1.79 Å
- 8J6H chain A against the predicted model Q99312: TM-score 0.94, RMSD 1.76 Å
- 8J6H chain C against the predicted model Q99312: TM-score 0.94, RMSD 2.08 Å
- 8J6H chain D against the predicted model Q99312: TM-score 0.93, RMSD 1.87 Å
Elsewhere
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