UniProt Q97Z79
Translation initiation factor 2 subunit alpha (Q97Z79)
Translation initiation factor 2 subunit alpha (UniProt Q97Z79): 16 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q97Z79
- Protein
- Translation initiation factor 2 subunit alpha
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
17 records of Q97Z79 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2AHO | Structure of the archaeal initiation factor eIF2 alpha-gamma heterodimer from Sulfolobus… | x-ray diffraction | B | — | — |
| 2AHO | Structure of the archaeal initiation factor EIF2 alpha-gamma heterodimer from sulfolobus… | x-ray diffraction | B | — | — |
| 2QMU | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the… | x-ray diffraction | B | — | — |
| 2QMU | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the… | x-ray diffraction | B | — | — |
| 2QN6 | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the… | x-ray diffraction | B | — | — |
| 2QN6 | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the… | x-ray diffraction | B | — | — |
| 3CW2 | Crystal structure of the intact archaeal translation initiation factor 2 from Sulfolobus… | x-ray diffraction | C, D, G, H | — | — |
| 3CW2 | Crystal structure of the intact archaeal translation initiation factor 2 from sulfolobus… | x-ray diffraction | C, D, G, H | — | — |
| 3QSY | Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea | x-ray diffraction | B | — | — |
| 3QSY | Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in archaea | x-ray diffraction | B | — | — |
| 3V11 | Structure of the ternary initiation complex AIF2:GDPNP:methionylated initiator TRNA | x-ray diffraction | B | — | — |
| 3V11 | Structure of the ternary initiation complex AIF2:GDPNP:METHIONYLATED initiator tRNA | x-ray diffraction | B | — | — |
| 6SW9 | IC2A model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid… | electron microscopy | 9 | — | — |
| 6SW9 | IC2A model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid… | electron microscopy | 9 | — | — |
| 6SWC | IC2B model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid… | electron microscopy | 9 | — | — |
| 6SWC | IC2B model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid… | electron microscopy | 9 | — | — |
| Q97Z79 | AlphaFold monomer V2.0 prediction for translation initiation factor 2 subunit alpha (Q97Z79) | predicted | A | — | 1 (best 0.52) |
Experiment against prediction
- 2QN6 chain B against the predicted model Q97Z79: TM-score 0.97, RMSD 0.59 Å
- 2QN6 chain B against the predicted model Q97Z79: TM-score 0.97, RMSD 0.59 Å
- 2QMU chain B against the predicted model Q97Z79: TM-score 0.94, RMSD 1.08 Å
- 2QMU chain B against the predicted model Q97Z79: TM-score 0.94, RMSD 1.08 Å
- 3V11 chain B against the predicted model Q97Z79: TM-score 0.81, RMSD 2.97 Å
- 3V11 chain B against the predicted model Q97Z79: TM-score 0.81, RMSD 2.97 Å
- 3QSY chain B against the predicted model Q97Z79: TM-score 0.74, RMSD 2.34 Å
- 3QSY chain B against the predicted model Q97Z79: TM-score 0.74, RMSD 2.34 Å
- 3CW2 chain C against the predicted model Q97Z79: TM-score 0.68, RMSD 3.03 Å
- 3CW2 chain C against the predicted model Q97Z79: TM-score 0.68, RMSD 3.03 Å
Elsewhere
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