UniProt Q96RD6
Pannexin-2 (Q96RD6)
Pannexin-2 (UniProt Q96RD6): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 65 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96RD6
- Protein
- Pannexin-2
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 65 · 4 records with a druggable one
Structures
4 records of Q96RD6 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7XLB | Cryo-EM structure of human pannexin 2 | electron microscopy | E, A, B, C, D, F, G | — | 20 (best 0.85) |
| 8F7C | Cryo-EM structure of human pannexin 2 | electron microscopy | A, B, C, D, E, F, G | — | 20 (best 0.77) |
| 8GYQ | Cryo-EM structure of human Pannexin-2 in pre-open state. | electron microscopy | A, B, C, D, E, F, G | NAG | 20 (best 0.65) |
| Q96RD6 | AlphaFold monomer V2.0 prediction for pannexin-2 (Q96RD6) | predicted | A | — | 5 (best 0.72) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
Experiment against prediction
- 8GYQ chain A against the predicted model Q96RD6: TM-score 0.90, RMSD 2.47 Å
- 7XLB chain E against the predicted model Q96RD6: TM-score 0.89, RMSD 2.67 Å
- 8F7C chain A against the predicted model Q96RD6: TM-score 0.88, RMSD 2.44 Å
- 8F7C chain F against the predicted model P0ABE7: TM-score 0.26, RMSD 3.94 Å
- 8F7C chain B against the predicted model P0ABE7: TM-score 0.26, RMSD 3.98 Å
- 8F7C chain E against the predicted model P0ABE7: TM-score 0.26, RMSD 3.99 Å
- 8F7C chain G against the predicted model P0ABE7: TM-score 0.26, RMSD 3.99 Å
- 8F7C chain A against the predicted model P0ABE7: TM-score 0.26, RMSD 3.98 Å
- 8F7C chain C against the predicted model P0ABE7: TM-score 0.26, RMSD 3.99 Å
- 8F7C chain D against the predicted model P0ABE7: TM-score 0.26, RMSD 4.04 Å
Elsewhere
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