UniProt Q96QV6

Histone H2A type 1-A (Q96QV6)

Histone H2A type 1-A (UniProt Q96QV6): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q96QV6
Protein: Histone H2A type 1-A
Experimental structures: 4
Predicted models: 1
Ligands: 2
Pockets: 21 · 2 records with a druggable one

Structures

5 records of Q96QV6 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5GSU	Crystal structure of nucleosome core particle consisting of human testis-specific histone variants…	x-ray diffraction	C, G	CL, MN	10 (best 0.81)
5GSU	Crystal structure of nucleosome core particle consisting of human testis-specific histone variants…	x-ray diffraction	C, G	—	—
5GT0	Crystal structure of nucleosome complex with human testis-specific histone variants, Th2a	x-ray diffraction	C, G	MN	11 (best 0.80)
5GT0	Crystal structure of nucleosome complex with human testis-specific histone variants, TH2A	x-ray diffraction	C, G	—	—
Q96QV6	AlphaFold monomer V2.0 prediction for histone H2A type 1-a (Q96QV6)	predicted	A	—	—

Ligands

MN · Manganese (II) ion · in 2 records
CL · Chloride ion · in 1 record

Experiment against prediction

5GT0 chain C against the predicted model Q96QV6: TM-score 0.96, RMSD 0.79 Å
5GT0 chain C against the predicted model Q96QV6: TM-score 0.96, RMSD 0.79 Å
5GSU chain G against the predicted model Q96QV6: TM-score 0.96, RMSD 0.81 Å
5GSU chain G against the predicted model Q96QV6: TM-score 0.96, RMSD 0.81 Å
5GSU chain C against the predicted model Q96QV6: TM-score 0.95, RMSD 0.91 Å
5GSU chain C against the predicted model Q96QV6: TM-score 0.95, RMSD 0.91 Å
5GT0 chain G against the predicted model Q96QV6: TM-score 0.95, RMSD 0.99 Å
5GT0 chain G against the predicted model Q96QV6: TM-score 0.95, RMSD 0.99 Å

Elsewhere

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