UniProt Q96N11
Integrator complex subunit 15 (Q96N11)
Integrator complex subunit 15 (UniProt Q96N11): 8 experimental structures and 1 predicted model on GenesisL1, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96N11
- Protein
- Integrator complex subunit 15
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 32 · 8 records with a druggable one
Structures
9 records of Q96N11 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8RBX | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | electron microscopy | o | — | — |
| 8RBZ | Structure of Integrator-PP2A-SOSS-CTD post-termination complex | electron microscopy | o | — | 2 (best 0.83) |
| 8RC4 | Structure of Integrator-PP2A complex | electron microscopy | o | — | 2 (best 0.80) |
| 9EOF | Structure of the human INTS5/8/10/15 subcomplex | electron microscopy | C | — | 5 (best 0.76) |
| 9EP1 | Structure of the Integrator arm module containing INTS10/13/14/15 subunits (state 2) | electron microscopy | C | — | 6 (best 0.76) |
| 9EP4 | Structure of Integrator subcomplex INTS5/8/15 | electron microscopy | D | — | 3 (best 0.57) |
| 9FA4 | Structure of the Integrator arm module containing subunits INTS10/13/14/15 (state 1) | electron microscopy | C | — | 5 (best 0.76) |
| 9FA7 | Structure of the Integrator arm module containing subunits INTS10/13/14/15 (state 3) | electron microscopy | C | — | 3 (best 0.66) |
| Q96N11 | AlphaFold monomer V2.0 prediction for uncharacterized protein C7ORF26 (Q96N11) | predicted | A | — | 6 (best 0.70) |
Experiment against prediction
- 9FA7 chain C against the predicted model Q96N11: TM-score 1.00, RMSD 0.43 Å
- 9EP1 chain C against the predicted model Q96N11: TM-score 1.00, RMSD 0.49 Å
- 9FA4 chain C against the predicted model Q96N11: TM-score 0.99, RMSD 0.49 Å
- 9EOF chain C against the predicted model Q96N11: TM-score 0.98, RMSD 1.00 Å
- 9EP4 chain D against the predicted model Q96N11: TM-score 0.98, RMSD 1.08 Å
- 8RBX chain o against the predicted model Q96N11: TM-score 0.91, RMSD 2.36 Å
- 8RBZ chain o against the predicted model Q96N11: TM-score 0.87, RMSD 2.96 Å
- 8RC4 chain o against the predicted model Q96N11: TM-score 0.82, RMSD 3.71 Å
Elsewhere
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