UniProt Q96LB2
Mas-related G-protein coupled receptor member X1 (Q96LB2)
Mas-related G-protein coupled receptor member X1 (UniProt Q96LB2): 4 experimental structures on GenesisL1, 1 ligand bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q96LB2
- Protein
- Mas-related G-protein coupled receptor member X1
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 13 · 3 records with a druggable one
Structures
4 records of Q96LB2 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8DWC | CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22 | electron microscopy | R | — | 5 (best 0.70) |
| 8DWH | CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16 | electron microscopy | R | U2U | 5 (best 0.70) |
| 8HJ5 | Cryo-EM structure of Gq-coupled MRGPRX1 bound with Compound-16 | electron microscopy | F | U2U | 3 (best 0.72) |
| Q96LB2 | AlphaFold monomer V2.0 prediction for mas-related G-protein coupled receptor member X1 (Q96LB2) | — | — | — |
Ligands
- U2U · N-{2-[(1-aminoisoquinolin-6-yl)oxy]-4-methylphenyl}-2-methoxybenzene-1-sulfonamide · in 2 records
Experiment against prediction
- 8HJ5 chain F against the predicted model P0ABE7: TM-score 0.27, RMSD 4.35 Å
Elsewhere
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