UniProt Q96HY6
DDRGK domain-containing protein 1 (Q96HY6)
DDRGK domain-containing protein 1 (UniProt Q96HY6), EC 2.3.2.-: 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q96HY6
- Protein
- DDRGK domain-containing protein 1
- EC
- 2.3.2.-
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 2 records with a druggable one
Structures
8 records of Q96HY6 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7W3N | Crystal structure of Ufm1 fused to UFBP1 UFIM | x-ray diffraction | A | — | — |
| 8B9X | Chimeric protein of human UFM1 E3 ligase, UFL1, and DDRGK1 | x-ray diffraction | A, B | CL | 2 (best 0.37) |
| 8C0D | UFL1/DDRGK1 bound to UFC1 | x-ray diffraction | B, E | — | 6 (best 0.62) |
| 8OHD | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) | electron microscopy | C | — | — |
| 8OJ0 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | electron microscopy | C | — | — |
| 8OJ5 | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) | electron microscopy | C | — | — |
| 8QFC | UFL1 E3 ligase bound 60S ribosome | electron microscopy | D | — | 4 (best 0.58) |
| Q96HY6 | AlphaFold monomer V2.0 prediction for ddrgk domain-containing protein 1 (Q96HY6) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 1 record
Experiment against prediction
- 7W3N chain A against the predicted model P61960: TM-score 0.82, RMSD 1.16 Å
- 8OJ0 chain C against the predicted model Q96HY6: TM-score 0.83, RMSD 2.42 Å
- 8C0D chain E against the predicted model Q96HY6: TM-score 0.76, RMSD 2.13 Å
- 8C0D chain B against the predicted model Q96HY6: TM-score 0.75, RMSD 2.46 Å
- 8B9X chain A against the predicted model O94874: TM-score 0.60, RMSD 2.07 Å
- 8B9X chain B against the predicted model O94874: TM-score 0.60, RMSD 2.06 Å
- 8QFC chain D against the predicted model Q96HY6: TM-score 0.57, RMSD 2.86 Å
- 8OHD chain C against the predicted model Q96HY6: TM-score 0.55, RMSD 4.07 Å
- 8OJ5 chain C against the predicted model Q96HY6: TM-score 0.55, RMSD 4.06 Å
- 7W3N chain A against the predicted model Q96HY6: TM-score 0.36, RMSD 3.58 Å
Elsewhere
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