UniProt Q96HS1
Serine/threonine-protein phosphatase PGAM5, mitochondrial (Q96HS1)
Serine/threonine-protein phosphatase PGAM5, mitochondrial (UniProt Q96HS1), EC 3.1.3.16: 13 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, druggability and experiment…
- UniProt
- Q96HS1
- Protein
- Serine/threonine-protein phosphatase PGAM5, mitochondrial
- EC
- 3.1.3.16
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 1 record with a druggable one
Structures
14 records of Q96HS1 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3MXO | Crystal structure oh human phosphoglycerate mutase family member 5 (PGAM5) | x-ray diffraction | A, B | — | — |
| 3MXO | Crystal structure oh human phosphoglycerate mutase family member 5 (PGAM5) | x-ray diffraction | A, B | — | — |
| 3O0T | Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in complex with phosphate | x-ray diffraction | A, B | — | — |
| 3O0T | Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in complex with phosphate | x-ray diffraction | A, B | — | — |
| 5MUF | Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in its enzymatically… | x-ray diffraction | A, B, C | PO4 | — |
| 5MUF | Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in its enzymatically… | x-ray diffraction | A, B, C | PO4 | — |
| 6CNI | Crystal structure of H105A PGAM5 dimer | x-ray diffraction | A, B | NA, PO4 | — |
| 6CNL | Crystal Structure of H105A PGAM5 Dodecamer | x-ray diffraction | A, C, L, J, F, H, K, D, B, I, G, E | MG | 20 (best 0.64) |
| 6CNL | Crystal structure of H105A PGAM5 dodecamer | x-ray diffraction | A, C, L, J, F, H, K, D, B, I, G, E | MG | — |
| 7QAL | Three-dimensional structure of the PGAM5 C12L mutant tmd | solution nmr | A | — | — |
| 7QAM | Three-dimensional structure of the PGAM5 wt tmd | solution nmr | A | — | — |
| 7QAO | Three-dimensional structure of the PGAM5 C12S mutant tmd | solution nmr | A | — | — |
| 7QAP | Three-dimensional structure of the PGAM5 G17L mutant tmd | solution nmr | A | — | — |
| Q96HS1 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase PGAM5, mitochondrial… | predicted | A | — | 3 (best 0.39) |
Ligands
Experiment against prediction
- 6CNL chain I against the predicted model Q96HS1: TM-score 1.00, RMSD 0.32 Å
- 6CNL chain I against the predicted model Q96HS1: TM-score 1.00, RMSD 0.32 Å
- 5MUF chain C against the predicted model Q96HS1: TM-score 1.00, RMSD 0.38 Å
- 5MUF chain C against the predicted model Q96HS1: TM-score 1.00, RMSD 0.38 Å
- 6CNL chain K against the predicted model Q96HS1: TM-score 1.00, RMSD 0.36 Å
- 6CNL chain K against the predicted model Q96HS1: TM-score 1.00, RMSD 0.36 Å
- 6CNL chain G against the predicted model Q96HS1: TM-score 0.99, RMSD 0.37 Å
- 6CNL chain G against the predicted model Q96HS1: TM-score 0.99, RMSD 0.37 Å
- 6CNL chain L against the predicted model Q96HS1: TM-score 0.99, RMSD 0.39 Å
- 6CNL chain L against the predicted model Q96HS1: TM-score 0.99, RMSD 0.39 Å
Elsewhere
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