UniProt Q96EY7
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (Q96EY7)
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (UniProt Q96EY7): 14 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q96EY7
- Protein
- Pentatricopeptide repeat domain-containing protein 3, mitochondrial
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 10 records with a druggable one
Structures
15 records of Q96EY7 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J9M | Structure of the human mitochondrial ribosome (class 1) | electron microscopy | A4 | — | — |
| 6NU2 | Structural insights into unique features of the human mitochondrial ribosome recycling | electron microscopy | A4 | — | — |
| 6VLZ | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) | electron microscopy | A4 | — | 1 (best 0.87) |
| 6ZS9 | Human mitochondrial ribosome in complex with ribosome recycling factor | electron microscopy | A4 | — | — |
| 6ZSB | Human mitochondrial ribosome in complex with mRNA and P-site tRNA | electron microscopy | A4 | — | — |
| 6ZSC | Human mitochondrial ribosome in complex with E-site tRNA | electron microscopy | A4 | — | 1 (best 0.89) |
| 6ZSG | Human mitochondrial ribosome in complex with mRNA, A-site tRNA, P-site tRNA and E-site tRNA | electron microscopy | A4 | — | 2 (best 0.89) |
| 7QI6 | Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution | electron microscopy | A4 | — | 1 (best 0.86) |
| 8CST | Human mitochondrial small subunit assembly intermediate (State E) | electron microscopy | 4 | — | — |
| 8CSU | Human mitochondrial small subunit assembly intermediate (State C*) | electron microscopy | 4 | — | 2 (best 0.86) |
| 8K2A | Cryo-EM structure of the human 55S mitoribosome with Tigecycline | electron microscopy | So | — | 1 (best 0.85) |
| 8OIR | 55S human mitochondrial ribosome with mtRF1 and P-site tRNA | electron microscopy | Ae | K | 1 (best 0.85) |
| 8OIS | 28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | Ae | K | 1 (best 0.85) |
| 8QRK | mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 1 | electron microscopy | 4 | — | 2 (best 0.86) |
| Q96EY7 | AlphaFold monomer V2.0 prediction for pentatricopeptide repeat domain-containing protein 3… | predicted | A | — | 5 (best 0.71) |
Ligands
- K · Potassium ion · in 2 records
Experiment against prediction
- 8K2A chain So against the predicted model Q96EY7: TM-score 1.00, RMSD 0.41 Å
- 8CSU chain 4 against the predicted model Q96EY7: TM-score 0.99, RMSD 0.82 Å
- 8CST chain 4 against the predicted model Q96EY7: TM-score 0.99, RMSD 0.83 Å
- 8OIR chain Ae against the predicted model Q96EY7: TM-score 0.97, RMSD 1.45 Å
- 8OIS chain Ae against the predicted model Q96EY7: TM-score 0.97, RMSD 1.45 Å
- 8QRK chain 4 against the predicted model Q96EY7: TM-score 0.97, RMSD 1.47 Å
- 7QI6 chain A4 against the predicted model Q96EY7: TM-score 0.97, RMSD 1.49 Å
- 6ZSB chain A4 against the predicted model Q96EY7: TM-score 0.94, RMSD 2.10 Å
- 6ZSC chain A4 against the predicted model Q96EY7: TM-score 0.94, RMSD 2.10 Å
- 6ZSG chain A4 against the predicted model Q96EY7: TM-score 0.94, RMSD 2.10 Å
Elsewhere
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