UniProt Q96EQ9
Histone-lysine N-methyltransferase PRDM9 (Q96EQ9)
Histone-lysine N-methyltransferase PRDM9 (UniProt Q96EQ9): 2 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96EQ9
- Protein
- Histone-lysine N-methyltransferase PRDM9
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
3 records of Q96EQ9 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C1Q | Crystal structure of the PRDM9 SET domain in complex with H3K4me2 and AdoHcy. | x-ray diffraction | A, B | — | — |
| 4C1Q | Crystal structure of the PRDM9 set domain in complex with H3K4ME2 and adohcy. | x-ray diffraction | A, B | — | — |
| Q96EQ9 | AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase PRDM9 (Q96EQ9) | predicted | A | — | 4 (best 0.70) |
Experiment against prediction
- 4C1Q chain B against the predicted model Q96EQ9: TM-score 0.96, RMSD 1.42 Å
- 4C1Q chain B against the predicted model Q96EQ9: TM-score 0.96, RMSD 1.42 Å
- 4C1Q chain A against the predicted model Q96EQ9: TM-score 0.90, RMSD 1.99 Å
- 4C1Q chain A against the predicted model Q96EQ9: TM-score 0.90, RMSD 1.99 Å
Elsewhere
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