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UniProt Q96C45

Serine/threonine-protein kinase ULK4 (Q96C45)

Serine/threonine-protein kinase ULK4 (UniProt Q96C45), EC 2.7.11.1: 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction…

UniProt
Q96C45
Protein
Serine/threonine-protein kinase ULK4
EC
2.7.11.1
Experimental structures
3
Predicted models
1
Ligands
2
Pockets
12 · 2 records with a druggable one

Structures

4 records of Q96C45 in the MolNFT archive: 3 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6TSZThe ULK4 pseudokinase domain bound to atpgammasx-ray diffractionUAGS—
6U5LStructure of human ULK4 in complex with an inhibitorx-ray diffractionA3RJ2 (best 0.66)
6U5LStructure of human ULK4 in complex with an inhibitorx-ray diffractionA3RJ—
Q96C45AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase ULK4 (Q96C45)predictedA—10 (best 0.69)

Ligands

  • 3RJ · N~2~-(1H-benzimidazol-6-yl)-N~4~-(5-cyclobutyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine · in 2 records
  • AGS · Phosphothiophosphoric acid-adenylate ester · in 1 record

Experiment against prediction

Elsewhere

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